4-(2-aminoethyl)-5-(18F)fluoranylbenzene-1,2-diol
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4-(2-aminoethyl)-5-(18F)fluoranylbenzene-1,2-diol
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CAS No:
107610-25-3
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Formula:
C8H10FNO2
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Chemical Name:
4-(2-aminoethyl)-5-(18F)fluoranylbenzene-1,2-diol
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Synonyms:
6-Fluorodopamine F-18;UNII-S30483Y0LT;S30483Y0LT;6-(18F)-Fluorodopamine;4-(2-aminoethyl)-5-fluoranylbenzene-1,2-diol;3,4-Dihydroxy-6-fluorophenethylamine F-18;107610-25-3;1,2-Benzenediol, 4-(2-aminoethyl)-5-(fluoro-18F)-;SCHEMBL12557128;MOLI000500;MOLI001345;MOLI001472;Q27288507
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CAS No:
Description
Fluorine F-18 6-Fluorodopamine is a radioconjugate consisting of 6-fluorodopamine labeled with fluorine F18 (6-[18F]FDA), with potential diagnostic activity. Upon administration, 6-[18F]FDA is taken up by presynaptic sympathetic nerve endings via the norepinephrine transporter (NET) uptake-1. Once inside, 6-[18F]FDA is rapidly converted by dopamine-beta-hydroxylase into 6-[18F]fluoronorepinephrine (6-[18F]FNE) and stored into neuronal storage vesicles. Upon positron emission tomographic (PET) scanning of the F18, sympathetic innervated regions can be visualized, such as those in pheochromocytoma.
4-(2-aminoethyl)-5-(18F)fluoranylbenzene-1,2-diol Basic Attributes
170.17 g/mol
170.072091 g/mol
S30483Y0LT
C91706
Computed Properties
Molecular Weight:170.17
XLogP3:0.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:170.072091
Monoisotopic Mass:170.072091
Topological Polar Surface Area:66.5
Heavy Atom Count:12
Complexity:145
Isotope Atom Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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