Aminoguanidine
-
Aminoguanidine
structure -
-
CAS No:
79-17-4
-
Formula:
CH6N4
-
Chemical Name:
Aminoguanidine
-
Synonyms:
Hydrazinecarboximidamide;Guanidine,amino-;Aminate base;Aminoguanidine;Guanylhydrazine;Monoaminoguanidine;Carbamimidic acid,hydrazide;Pimagedine;10331-66-5;146396-78-3;1608481-17-9
-
CAS No:
Description
ChEBI: A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Aminoguanidine is a one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide. It has a role as an EC 1.4.3.4 (monoamine oxidase) inhibitor and an EC 1.14.13.39 (nitric oxide synthase) inhibitor. It is a member of guanidines and a one-carbon compound.|Pimagedine has been developed by Synvista Therapeutics, Inc for the treatment of diabetic kidney disease. It is an advanced glycation end product inhibitor which manages diabetic nephropathy, either alone or in combination with other therapies. It is beneficial in treating patients with diabetic nephropathy.
Drug Information
Investigated for use/treatment in diabetic kidney disease.
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. (See all compounds classified as Enzyme Inhibitors.)
Pimagedine reportedly inhibits the formation of glycosylated proteins (advanced glycosylation end-products) and has other actions including inhibition of aldose reductase.
aminoguanidine
Computed Properties
Molecular Weight:74.09
XLogP3:-1.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:2
Exact Mass:74.059246208
Monoisotopic Mass:74.059246208
Topological Polar Surface Area:90.4
Heavy Atom Count:5
Complexity:41.6
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Learn More Other Chemicals
-
Aminoguanidine nitrate
10308-82-4
-
Aminoguanidine bicarbonate
2582-30-1
-
Aminoguanidine hydrochloride
16139-18-7
-
Aminoguanidine hemisulfate Formula
996-19-0
-
Aminoguanidine carbonate Formula
2200-97-7