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Iodoethane

Iodoethane structure

CAS No:
75-03-6
Formula:
C2H5I
Chemical Name:
Iodoethane
Synonyms:
10doethane(ethyliodide);Ethane, iodo-;Ethane,iodo-;ethaneiodide;IODOETHANE , STABILIZED WITH COPPER;Iodoethane (stabilized with Copper chip);ETHYL IODIDE extrapure;Iodoethane, 98%, stabilized with silver, pure
Categories:
Organic Chemistry > Hydrocarbons and Derivatives

Description

Colorless to yellow liquid. Iodoethane is a stable chemical substance. It is incompatible with strong bases, magnesium, and strong oxidising agents and gets discoloured when exposed to light, moisture, and air.

Liquid|COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. TURNS DARK ON EXPOSURE TO LIGHT.

Iodoethane is an iodoalkane that is ethane substituted by an iodo group. It derives from a hydride of an ethane.

A colorless liquid alkyl halide made by reaction of ethanol with iodine in the presence of red phosphorus.

Iodoethane also known as ethyl iodide is an alkyl iodide. The interaction of iodoethane with Pt(111) surfaces has been analyzed by using thermal desorption and X-ray photoelectron spectroscopy. Its microwave spectrum has been recorded and studied. The dynamics of the gas phase photolysis of iodoethane have been studied using resonance Raman spectra. Its thermodynamic characteristics in the ideal state have been reported.

Iodoethane Basic Attributes

Molecular Weight：

155.97

Exact Mass：

155.97

BRN：

505934

EC Number：

200-833-1

UNII：

59PO05D39L

ICSC Number：

0479

NSC Number：

8825

TSCA：

TSCA listed

DSSTox ID：

DTXSID9058783

Color/Form：

Clear colorless to faint yellow or pink

HScode：

2903 39 80

Characteristics

PSA：

XLogP3：

2.0

Appearance：

Clear colorless to faint yellow or pink Liquid

Density：

1.95 g/mL at 25 °C(lit.)

Melting Point：

-108 °C

Boiling Point：

69-73 °C(lit.)

Flash Point：

53 °C

Refractive Index：

n20/D1.513(lit.)

Water Solubility：

4 g/L (20 ºC)

Storage Conditions：

Store at R.T.

Vapor Pressure：

100 mm Hg ( 18 °C)

Vapor Density：

5.38 (vs air)

Toxicity：

Abdominal cavity-rat LD50: 330 mg/kg; abdominal cavity-mouse LD50: 560 mg/kg

Flammability characteristics：

Open flame, high heat and combustible; high heat decomposition or reaction with water and oxidant to generate toxic iodide gas

Odor：

light delicate odor

Henrys Law Constant：

1.4×10-3mol/(m3Pa) at 25℃, Burkholder et al. (2019)

Physical Dangers：

The vapour is heavier than air.

Critical Temperature & Pressure：

Store below +30°C.

Safety Information

Packing level：

III

Hazard category：

6.1

Transport codes：

2922

wgk germany：

hazard class code：

Xn,T

safety instructions：

23-26-36/37-45-37/39-16-36/37/39-27

RTECS Number：

KI4750000

Marks：

Xn,T

Storage features：

Treasury is ventilated at low temperature and dry; stored separately from oxidants and food additives

Precautionary statement(s)：

P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P272, P280, P285, P301+P312, P302+P352, P303+P361+P353, P304+P312, P304+P340, P304+P341, P305+P351+P338, P312, P321, P322, P330, P332+P313, P333+P313, P337+P313, P342+P311, P362, P363, P370+P378, P403+P233, P403+P235, P405, P501

Hazard Statements：

Toxic by inhalation and skin absorption, narcotic in high concentration.

RIDADR：

2922

Fire Hazards：

Flammable. Above 61 °C explosive vapour/air mixtures may be formed.

GHS Classification：

|Danger|H226 (13.93%): Flammable liquid and vapor [Warning Flammable liquids]|P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P272, P280, P285, P301+P312, P302+P352, P303+P361+P353, P304+P312, P304+P340, P304+P341, P305+P351+P338, P312, P321, P330, P332+P313, P333+P313, P337+P313, P342+P311, P362, P363, P370+P378, P403+P233, P403+P235, P405, and P501|Aggregated GHS information provided by 122 companies from 14 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Fire Fighting：

Use water spray, powder, foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.

Spillage Disposal：

Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Remove all ignition sources. Collect leaking and spilled liquid in covered containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

Safe Storage：

Fireproof. Separated from strong bases and strong oxidants.

Inhalation Risk：

No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.

Effects of Short Term Exposure：

The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the central nervous system. This may result in lowering of consciousness.

Fire Prevention：

NO open flames, NO sparks and NO smoking. Above 61 °C use a closed system, ventilation and explosion-proof electrical equipment.

Inhalation Prevention：

Use ventilation, local exhaust or breathing protection.

Skin Prevention：

Protective gloves. Protective clothing.

Eye Prevention：

Wear safety goggles, face shield or eye protection in combination with breathing protection.

Toxicity

Toxicity class：

highly toxic

Drug Information

Metabolism/Metabolites：

1-iodoethane has known human metabolites that include ethylglutathione.

First Aid：

Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.

Rinse skin with plenty of water or shower. Refer for medical attention .

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

MeSH Entry Terms：

iodoethane

Exposure Routes：

The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion.

Symptoms：

Confusion. Cough. Drowsiness. Dizziness. Shortness of breath. Sore throat. Unconsciousness.

Redness. Pain.

Iodoethane Use and Manufacturing

Methods of Manufacturing

Derived from the reaction of ethanol and phosphorus triiodide. Put industrial ethanol and red phosphorus in the reaction bottle, heat and reflux on a water bath, and slowly add iodine particles. After completion, continue to reflux for 3h. Then the reaction solution was distilled to distill out the crude yellow product, washed and dried to obtain the finished product. In addition, the addition of ethylene and hydrogen iodide can also produce ethyl iodide.

Uses

A useful synthetic reagent for the introduction of ethyl groups

Paint additives and coating additives not described by other categories

Iodoethane is an excellent ethylating agent used in organic synthesis to introduce an ethyl group into a compound. It reacts with magnesium to form the Grignard reagent, ethylmagnesium iodide which is used in organic synthesis. It is involved in the preparation of 1-ethyl-3-nitro-2-phenyl-indole and also serves as hydrogen radical promoter.

Manufacturing Info：

Plastic material and resin manufacturing|Ethane, iodo-: ACTIVE

Computed Properties

Molecular Weight:155.97
XLogP3:2.1
Exact Mass:155.94360
Monoisotopic Mass:155.94360
Heavy Atom Count:3
Complexity:2.8
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Tetraphosphorus

Triethyl phosphite

Ethanol

Downstream Products

1,2-Diethoxybenzene

Benzoyl chloride

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Iodoethane CAS 75-03-6

CAS No.: 75-03-6

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High Quality Iodoethane CAS NO.75-03-6

CAS No.: 75-03-6

Grade: Pharmaceutical Grade

Content: 99%

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