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    1-Indanone structure

    1-Indanone

    • CAS No:

      83-33-0

    • Formula:

      C9H8O

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    Description

    Pale yellow liquid

    Basic Attributes

    • 83-33-0

    • C9H8O

    • 132.16

    • 132.057510

    • 17.1

    • 1.7

    • 201-470-1

    • QNXSIUBBGPHDDE-UHFFFAOYSA-N

    • 1

    • 0

    • 0.22

    • 0

    Characteristics

    • Light yellow to brown Crystalline Mass

    • 1.1±0.1 g/cm3

    • 38-40 °C(lit.)

    • 243-245 °C(lit.)

    • 233 °F

    • 1.585

    • H2O: 6.5 g/L (20 C)

    • -20°C

    • 507957

    Safety Information

    • II; III

    • 4.1

    • 29143900

    • NONH for all modes of transport

    • 3

    • 22-36/37/38

    • 22-24/25-36-26

    • Xn,Xi

    • P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, P501

    • H302

    • Irritant

    Product Usage

    1-Indanone is an oxidation product of Indan, a component of fuels, solvents, and varnishes. 1-Indanone is also a metabolite of Thalidomide that has been shown to inhibit the attachment of tumor cells to concanavalin A coated plastic surfaces.

    Production Methods

    The dried hydrogen chloride was passed into freshly steamed indene, the temperature was kept at 5-10°C, the reaction required 8-10h, the reaction product was distilled under reduced pressure, and 90-103 (1.73kPa) was collected to obtain α-chlorodihydroindene. It is oxidized with chromium trioxide in glacial acetic acid, and the temperature is kept at 35-40°C, that is, dihydro-1-indanone is formed. The yield is 50%-60%.

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