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1-Indanone
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CAS No:
83-33-0
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Formula:
C9H8O
Request for Quotation -
CAS No:
Basic Attributes
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83-33-0
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C9H8O
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132.16
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132.057510
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17.1
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1.7
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201-470-1
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QNXSIUBBGPHDDE-UHFFFAOYSA-N
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1
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0
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0.22
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0
Characteristics
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Light yellow to brown Crystalline Mass
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1.1±0.1 g/cm3
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38-40 °C(lit.)
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243-245 °C(lit.)
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233 °F
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1.585
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H2O: 6.5 g/L (20 C)
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-20°C
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507957
Safety Information
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II; III
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4.1
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29143900
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NONH for all modes of transport
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3
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22-36/37/38
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22-24/25-36-26
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Xn,Xi
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P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, P501
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H302
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Irritant
Product Usage
1-Indanone is an oxidation product of Indan, a component of fuels, solvents, and varnishes. 1-Indanone is also a metabolite of Thalidomide that has been shown to inhibit the attachment of tumor cells to concanavalin A coated plastic surfaces.
Production Methods
The dried hydrogen chloride was passed into freshly steamed indene, the temperature was kept at 5-10°C, the reaction required 8-10h, the reaction product was distilled under reduced pressure, and 90-103 (1.73kPa) was collected to obtain α-chlorodihydroindene. It is oxidized with chromium trioxide in glacial acetic acid, and the temperature is kept at 35-40°C, that is, dihydro-1-indanone is formed. The yield is 50%-60%.