Essential oils, cassia

282.4

282.16198

616-916-4

29.5

1.041

1.03 g/mL at 25 °C(lit.)

194-234°C

197°F

1.5339

2-8°C

1 volume in 3 volumes of 70% ethanol at 20 °C (Cassia oil); 1 volume in 2 volumes of 70% ethanol at 20 °C (Cinnamon leaf oil); 1 volume in at least 3 volumes of 70% ethanol (Cinnamon bark oil)

2-8°C

Cinnamon bark oil contains as its major component cinnamaldehyde (usually 60-75%); other constituents include eugenol, eugenol acetate, cinnamyl acetate, cinnamyl alcohol, methyl eugenol, benzaldehyde, cuminaldehyde, benzyl benzoate, linalool, monoterpene hydrocarbons (e.g., pinene, phellandrene, and cymene), carophyllene, safrole ... Cinnamon leaf oil contains high concentrations of eugenol (Ceylon type 80-88%; Seychelles type 87-96%); it also contains many of the major constituents present in cinnamon bark oil (e.g., cinnamaldehyde, cinnamyl acetate, eugenol acetate, and benzaldehyde) as well as other minor compounds, including humulene, isocaryophyllene, alpha-ylangene, coniferaldehyde, methyl cinnamate, and ethyl cinnamate. A cinnamon leaf oil of Chinese origin ... is reported to contain only about 3% eugenol but with a high content (ca. 60%) of safrole.

UN 2810 6.1/PG 3

3

R21;R36/37/38;R43

S26;S36

FL6340000

Xn

DARKENS & THICKENS ON EXPOSURE TO AIR

P280-P305 + P351 + P338-P312

H311-H315-H319

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Essential oils, oleoresins (solvent-free), and natural extractives (including distillates) that are generally recognized as safe for their intended use, within the meaning of section 409 of the Act. Cinnamon bark and leaf (Ceylon, Chinese and Saigon) are included on this list.

|Danger|H311 (19.23%): Toxic in contact with skin [Danger Acute toxicity, dermal]|P261, P264, P272, P280, P302+P352, P305+P351+P338, P312, P321, P322, P332+P313, P333+P313, P337+P313, P361, P362, P363, P405, and P501|Aggregated GHS information provided by 261 companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

A human skin irritant.

LD50 Rat oral 2800 mg/kg|LD50 Mouse oral 2670 mg/kg|LD50 Mouse ip 500 mg/kg|LD50 Rabbit skin 320 mg/kg

Volatile oil from leaves & twigs of Cinnamomum cassia nees, Lauraceae. Constituent 80-90% cinnamaldehyde; cinnamyl acetate, eugenol.

... Cinnamon ... bark oils are frequently used either as ... carminative, stomachic, tonic, or counterirritants in pharmaceutical and cosmetic preparations ...|Cinnamon oil (presumably bark oil) has exhibited antifungal, antiviral, bactericidal, and larvicidal activities.

TOXICITY RATINGS: 3(?). 3= MODERATELY TOXIC: PROBABLE ORAL LETHAL DOSE (HUMAN) 0.5-5 G/KG; BETWEEN 1 OZ AND 1 PT (OR 1 LB) FOR 70 KG PERSON (150 LB). /CINNAMALDEHYDE/

THREE CASES OF ACUTE CONTACT SENSITIVITY TO A NEW TOOTHPASTE (CLOSE-UP). IN ALL CASES THERE WAS POSITIVE REACTION TO 0.5% CINNAMON OIL IN PETROLATUM.|IN EXPTL CONTACT SENSITIZATION TESTING IN HUMANS, ALCOHOL WAS MORE EFFECTIVE VEHICLE THAN PETROLATUM WHEN CINNAMON BARK OIL WAS USED IN PREDICTIVE TESTS.|ALLERGIC HAZARDS OF FLAVORING AGENTS SUCH AS CINNAMON OIL ARE DESCRIBED.|A 7 1/2 yr old boy ingested 2 oz.(about 60 mL) of oil of cinnamon and immediately felt a burning sensation in his mouth, chest, and stomach lasting for about 15 minutes. He then developed double vision, dizziness, vomiting, and collapse. Following ipecac and activated charcoal he developed diarrhea, more vomiting, dizziness, abdominal cramps, and burning in the rectal area. The white blood count was 29,800/cu mm. Gastrointestinal symptoms and sleepiness persisted for 5 hr.

CINNAMON WATER NF X11. CLEAR, SATURATED SOLUTION OF CINNAMON OIL IN PURIFIED WATER|TINCTURE (20% IN 60-75% ETHANOL), FLUID EXTRACT, ESSENTIAL OIL, OLEORESIN, POWDERED SPICE|Grades: USP (as cinnamon oil); Redistilled; Technical; Lead-free|PHENOL CONTENT (AS EUGENOL): 4-10%; ALDEHYDE CONTENT (AS CINNAMIC ALDEHYDE): 55-78% /CEYLON CINNAMON BARK OIL/|For more Formulations/Preparations (Complete) data for OIL OF CINNAMON (6 total), please visit the HSDB record page.

Cassia oil: ACTIVE|/CINNAMON/ CINNAMON BARK- CEYLON, SAIGON, & CHINESE: GRAS (I), (II); CINNAMON LEAF- CEYLON, SAIGON, & CHINESE: GRAS (II).|SINCE LEAD CONTAINERS ARE USUALLY USED WHEN OIL IS SHIPPED FROM CHINA, A TEST FOR HEAVY METALS IS NECESSARY.|THE POUNDS OF /CINNAMON CEYLON/ ESSENTIAL OIL NEEDED TO REPLACE 100 LB OF DRY COMMERCIAL QUALITY SPICE OR HERB IS 0.5 LB.|REPORTED USES: CINNAMON BARK OIL...IN...NON-ALCOHOLIC BEVERAGES 5.5 PPM; ICE CREAM, ICES, ETC 18 PPM; CANDY 80 PPM; BAKED GOODS 110 PPM; CHEWING GUM 620 PPM; CONDIMENTS 25 PPM; MEATS 50 PPM.|REPORTED USES: CINNAMON LEAF OIL...IN...NON-ALCOHOLIC BEVERAGES 6.8 PPM; ICE CREAM, ICES, ETC 3.4 PPM; CANDY 32 PPM; BAKED GOODS 54 PPM; GELATINS & PUDDINGS 0.20 PPM; CHEWING GUM 160-520 PPM; CONDIMENTS 20-78 PPM; PICKLES 32-48 PPM; SPICED FRUITS 3.0 PPM.

OFFICIAL FINAL ACTION. METHOD 1 & 2 DETERMINATION OF SPECIFIC GRAVITY; METHOD 3, GAS CHROMATOGRAPHY. 19.112. MEASUREMENT OF OIL USING BABCOCK MILK TEST BOTTLE.|AOAC 950.45. Alcohol in Cassia, Cinnamon, and Clove Extracts.|AOAC 932.10. Oil in Cassia, Cinnamon, and Clove Extracts.

Cosmetics -> Hair conditioning; Masking; Oral care