Schizophyllan
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Schizophyllan
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CAS No:
9050-67-3
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Chemical Name:
Schizophyllan
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Synonyms:
Schizophyllan;Sizofiran;Schizophyllane;Shizophyllan;SPG;Sixofilan;Sizofilan;Sonifilan;Schizophylan;Sizofuran
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CAS No:
Description
A beta-D-glucan obtained from the Aphyllophoral fungus Schizophyllum commune. It is used as an immunoadjuvant in the treatment of neoplasms, especially tumors found in the stomach.
Drug Information
Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity. (See all compounds classified as Adjuvants, Immunologic.)|Agents obtained from higher plants that have demonstrable cytostatic or antineoplastic activity. (See all compounds classified as Antineoplastic Agents, Phytogenic.)
Schizophyllan
Computed Properties
Molecular Weight:666.6
XLogP3:-7.9
Hydrogen Bond Donor Count:14
Hydrogen Bond Acceptor Count:21
Rotatable Bond Count:10
Exact Mass:666.22185834
Monoisotopic Mass:666.22185834
Topological Polar Surface Area:348
Heavy Atom Count:45
Complexity:918
Defined Atom Stereocenter Count:20
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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