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Pyruvate kinase

Pyruvate kinase structure

CAS No:
9001-59-6
Chemical Name:
Pyruvate kinase
Synonyms:
Pyruvate kinase;Kinase (phosphorylating),pyruvate;E.C. 2.7.1.40;Kinase (phosphorylating),fluoro-;Pyruvic kinase;Fluorokinase;EC 2.7.1.40;Phosphoenolpyruvate kinase;Pyruvate phosphotransferase (EC 2.7.1.40);Protein kinase Pyk;Pyruvate kinases;Pyruvic kinases;Pyruvate phosphotransferase;Pyruvate phosphotransferases;Fluorokinases
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

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Description

White powder

Pyruvate kinase Basic Attributes

Molecular Weight：

0.00000

Exact Mass：

226.106583

EC Number：

232-616-2

HScode：

35079090

Characteristics

PSA：

0.00000

XLogP3：

-2.17

Appearance：

white powder

Density：

1.4±0.1 g/cm3

Boiling Point：

656.2±55.0 °C at 760 mmHg

Flash Point：

350.7±31.5 °C

Refractive Index：

1.591

Water Solubility：

soluble in water ( 1mg/ml).

Storage Conditions：

2-8°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

Pyruvate kinase Use and Manufacturing

Methods of Manufacturing

Rabbit muscle is used as raw material, homogenized and extracted with water, and then fractionated and precipitated with ammonium sulfate and ethanol respectively. After heating to remove inactive proteins, it is again precipitated with ammonium sulfate and refined after recrystallization.

Uses

It is used for biochemical research and is often used as a diagnostic enzyme in clinical practice to determine adenosine diphosphate (ADP), adenosine monophosphate (AMP), phosphoenolpyruvate and phosphoglycerate.

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