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Thyrotropin

Thyrotropin structure

Thyrotropin 

structure
  • CAS No:

    9002-71-5

  • Chemical Name:

    Thyrotropin

  • Synonyms:

    Thyrotropin;Pretiron;Thyrotrophin;Thyrotropic hormone;Thytropar;TSH (hormone);TTH;Thyroid-stimulating hormone;Thyroid-stimulating factor;Dermathycin;TSH;Thyreotrophic hormone;Thyroid-stimulating hormones;Thyroid-stimulating factors;Thyreotrophic hormones;Thyrotropins;Thyrotropic hormones;9015-90-1;11006-84-1

  • Categories:

    Active Pharmaceutical Ingredients  >  Hormones and the Endocrine System

Description

A hormone secreted by the anterior lobe of the pituitary gland. It increases the rate of removal of iodine from the blood by the thyroid gland, synthesis of the thyroid hormone, and its release into the bloodstream. The thyrotropic hormone is a protein with a low molecular weight (about 10,000) that contains some carbohydrate.

Thyrotropin Basic Attributes

160.22

422.191376

232-664-4

Characteristics

41.8

1.55 (LogP)

lyophilized powder

118.0 °C

2-8°C

Safety Information

NONH for all modes of transport

3

XP3581600

B

Thyrotropin Use and Manufacturing

Application: TSH test, used with radioactive iodine to identify the lesions of patients with hypothyroidism; used for toxic adenomatous goiter, as an adjunct therapeutic agent to increase the intake of iodine. When radioactive iodine is used to treat thyroid cancer, it can also be used to improve the efficacy. Note: It can cause hyperthyroidism and increase the burden of the cardiovascular system. Heart disease patients and adrenal insufficiency are used with caution or disabled.

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