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Subtilisin

Subtilisin structure

CAS No:
9014-01-1
Chemical Name:
Subtilisin
Synonyms:
Subtilisin;E.C. 3.4.4.16;Subtilisin Carlsberg;Maxatase;ALK-enzyme;E.C. 3.4.21.14;EC 3.4.21.14;Bioprase;Colistinase;Proteinase,Bacillussubtilis alkaline;Thermoase PC 10;EC 3.4.4.16;Bacillus subtilis alk. proteinase;Bacillus subtilis alkaline proteinase;Peptidase,subtilo-,A;Bacillopeptidase A;Bacillopeptidase B;Bacillussubtilis Alkaline proteinase;SP 266;Superase;Nagarse;Savinase 4.0T;Savinase 8.0L;Savinase;Subtilopeptidase;Savinase 16.0L;Alcalase;Alcalase 0.6L;Kazusase;Protease XXVII;Protease VIII;Bioprase AL 15;Opticlean;Esperase;Orientase 10B;Bioprase APL 30;E.C. 3.4.21.62;EC 3.4.21.62;Protin A 3L;Genenase I;Alcalase 2.5L;Savinase 32.0 L-EX;Maxacal;Bioprase SP 20;Maxacal CX600K;Bioprase Conc;Bioprase PN 4;Savinase 16.0L-EX;Savinase 12T;ChiroCLEC-BL;Protin A;Savinase 4T;Chirazyme P 1;Alcalase 2.4L;Serine alkaline protease;Savinase 12.0T;Savinase 18.0T-W;Savinase L16 EX;Purafect L;Properase L;Extretex;Esperase 8.0L;Spezyme FAN;BLAP 260;BLAP S;Evertase 24 LDP;Bioprase SP;Genenase;Kannase;Savinase 16.0T;Esperase 8.0;Bioprase 30G;Orientase 22B;Properase;Savinase 6T;Alcalase 6.0T;Bioprase SP 4;Necrolytin G;Rohazym ML;Profezym;Maxacal L;APB-72;Bioprase SP 10;Novolan T;Bioblase SP-15 FG;M-Protease;ChiroCLEC CRO;Dafazyme PR B;Alcalase 2.0M;Properase 1000E;Validase TSP Concentrate II;Proleather FG-F;Purafect;Purafect OX;Maxatase XL;Protin A 10LF;Bioprase NYS;Savinase 16L;Protolichetrem;2392-42-9;9028-05-1;9031-73-6;9045-36-7;9063-47-2;9067-41-8;12626-20-9;12770-87-5;104645-85-4;148093-32-7;179530-31-5;196414-34-3;213972-06-6;1349805-21-5
Categories:
Cosmetic Ingredient > Skin Conditioning

Description

These are proteolytic enzymes which take the form of light-colored, free-flowing powders. A protein containing numerous amino acids

Subtilisin Basic Attributes

EC Number：

232-752-2

HScode：

35079090

Characteristics

Appearance：

white powder

Density：

1.3

Storage Conditions：

2-8°C

Toxicity：

Oral-rat LD50: 3700 mg/kg

Flammability characteristics：

Flammable; burning produces toxic nitrogen oxide fumes

Safety Information

Transport codes：

3082

wgk germany：

hazard class code：

37/38-41-42-36/37/38-50-22

safety instructions：

23-24-26-36/37/39-22-36/37-61-45-39

RTECS Number：

UK9540000

Marks：

Xn,N

Storage features：

Ventilated, low temperature and dry

Stability/Shelf Life：

store cold

Toxicity

Toxicity class：

moderately toxic

Subtilisin Use and Manufacturing

Methods of Manufacturing

It is produced by submerged fermentation of Baeillus licheni formis.

Uses

Proteolytic enzyme preparation. Mainly used in gelatin production, which can greatly shorten the extraction time. It is also used in the hydrolysis of vegetable protein, animal protein and fish protein.

Drug Function and Efficacy

Directly supplement normal physiological flora, inhibit pathogenic bacteria, promote digestion and absorption of nutrients, inhibit the production and absorption of enterogenic toxins, and adjust the imbalance of intestinal flora

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Bacillus subtilis and Enterococcus dual live bacteria multivitamin granules
Ingredients	This product is a compound preparation. Each bag (1 gram) contains 37.5 mg of live bacteria freeze-dried powder, including 150 million live bacteria [1.35×108 Enterococcus faecalis, 1.5×107 Bacillus subtilis], 10 mg of vitamin C, 0.5 mg of vitamin B1, 0.5 mg of vitamin B2, 0.5 mg of vitamin B6, 1.0 micrograms of vitamin B12, 2.0 mg of niacinamide, 20 mg of calcium lactate (equivalent to 2.6 mg of calcium), and 1.25 mg of zinc oxide (equivalent to 1.0 mg of zinc).
Indication	1. Taking this product with antibacterial drugs can weaken their efficacy and should be taken separately. 2. Bismuth, tannic acid, medicinal charcoal, tinctures, etc. can inhibit and adsorb live bacteria and should not be used together. 3. If used with other drugs at the same time, drug interactions may occur. Please consult a doctor or pharmacist for details.
Specifications	1g/bag

Bacillus subtilis combined with live bacteria enteric-coated capsules
Ingredients	This product is a compound preparation, and its main ingredients are: Each capsule (250mg) contains: 500 million live bacteria, including 4.5108 Enterococcus faecium and 5.0107 Bacillus subtilis.
Indication	Not yet clear.
Specifications	250mg/capsule
Manufacturer	Beijing Hanmi Pharmaceutical Co., Ltd.

Bacillus subtilis and Enterococcus dual live bacteria multivitamin granules
Ingredients	This product is a compound preparation. Each bag (1 gram) contains 37.5 mg of live bacteria freeze-dried powder, including 150 million live bacteria [1.35×108 Enterococcus faecalis, 1.5×107 Bacillus subtilis], 10 mg of vitamin C, 0.5 mg of vitamin B1, 0.5 mg of vitamin B2, 0.5 mg of vitamin B6, 1.0 micrograms of vitamin B12, 2.0 mg of niacinamide, 20 mg of calcium lactate (equivalent to 2.6 mg of calcium), and 1.25 mg of zinc oxide (equivalent to 1.0 mg of zinc).
Indication	1. Taking this product together with antibacterial drugs can weaken their efficacy and should be taken separately. 2. Bismuth, tannic acid, medicinal charcoal, tinctures, etc. can inhibit and adsorb live bacteria and cannot be used together. 3. If used with other drugs at the same time, drug interactions may occur. Please consult a doctor or pharmacist for details.
Specifications	1g/bag

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Guide of Subtilisin

Description
Basic Attributes
Characteristics
Safety Information
Toxicity
Use and Manufacturing
Drug Function and Efficacy
Related Drugs
Recommended Suppliers
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Subtilisin

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