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Cloprednol

Cloprednol structure

CAS No:
5251-34-3
Formula:
C21H25ClO5
Chemical Name:
Cloprednol
Synonyms:
Pregna-1,4,6-triene-3,20-dione,6-chloro-11,17,21-trihydroxy-,(11β)-;Pregna-1,4,6-triene-3,20-dione,6-chloro-11β,17,21-trihydroxy-;(11β)-6-Chloro-11,17,21-trihydroxypregna-1,4,6-triene-3,20-dione;Cloprednol;Synestan;Novacort;Cloradryn;RS 4691;Cloprednole
Categories:
Active Pharmaceutical Ingredients > Hormones and the Endocrine System

Description

Cloprednol is a 21-hydroxy steroid.|Cloprednol is a synthetic glucocorticoid that has been investigated for use in the treatment of asthma.

Cloprednol Basic Attributes

Molecular Weight：

392.876

Exact Mass：

392.87

EC Number：

226-052-6

UNII：

SYP56O3GJG

DSSTox ID：

DTXSID1022849

ATC Code：

H - Systemic hormonal preparations, excl. sex hormones and insulins

Characteristics

PSA：

94.8

XLogP3：

1.90010

Density：

1.4g/cm3

Boiling Point：

600.3ºC at 760mmHg

Flash Point：

316.9ºC

Refractive Index：

1.635

Safety Information

Precautionary statement(s)：

P260, P314, P501

Hazard Statements：

H373

GHS Classification：

|Warning|H373 (100%): Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]|P260, P314, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Drug Information

MeSH Entry Terms：

cloprednol

Cloprednol Use and Manufacturing

A systematic corticosteroid. Anti-inflammatory.

Computed Properties

Molecular Weight:392.9
XLogP3:1.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:392.1390516
Monoisotopic Mass:392.1390516
Topological Polar Surface Area:94.8
Heavy Atom Count:27
Complexity:813
Defined Atom Stereocenter Count:7
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes