3′,5′,3-Triiodothyronine
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3′,5′,3-Triiodothyronine
structure -
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CAS No:
5817-39-0
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Formula:
C15H12I3NO4
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Chemical Name:
3′,5′,3-Triiodothyronine
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Synonyms:
L-Tyrosine,O-(4-hydroxy-3,5-diiodophenyl)-3-iodo-;Alanine,3-[4-(4-hydroxy-3,5-diiodophenoxy)-3-iodophenyl]-,L-;O-(4-Hydroxy-3,5-diiodophenyl)-3-iodo-L-tyrosine;3,3′,5′-Triiodo-L-thyronine;3,3′,5′-Triiodothyronine;rT3;Reverse T3;Reverse triiodothyronine;3′,5′,3-Triiodothyronine;Reverse L-triiodothyronine;Isoliothyronine;3,3′,5′-L-Triiodothyronine;3,3′,5′-T3;(2S)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3-iodophenyl]propanoic acid;(S)-2-Amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3-iodophenyl)propanoic acid;(S)-2-Amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3-iodophenyl)propanoicacid;2820-50-0
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Categories:
Active Pharmaceutical Ingredients > Hormones and the Endocrine System
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CAS No:
Description
Beige Powder
3,3',5'-triiodo-L-thyronine is a 3,3',5'-triiodothyronine. It is a tautomer of a 3,3',5'-triiodo-L-thyronine zwitterion.|A metabolite of THYROXINE, formed by the peripheral enzymatic monodeiodination of T4 at the 5 position of the inner ring of the iodothyronine nucleus.
3′,5′,3-Triiodothyronine Basic Attributes
650.97
650.97
229-999-3
8NZ4Y08T96
DTXSID3046908
2922509090
Safety Information
UN1230 - class 3 - PG 2 - Methanol, solution
3
36/37/38-20/21/22-39/23/24/25-23/24/25-11
36-45-36/37-16
AY6750000
Xn,T,F
P210-P260-P280-P301 + P310 + P330-P302 + P352 + P312-P370 + P378
H225-H301 + H311 + H331-H370
|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P312, P322, P330, P363, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
3′,5′,3-Triiodothyronine Use and Manufacturing
One of the hormones produced by the thyroid gland that is involved in the maintenance of metabolic homeostasis. Also produced in peripheral tissues as the active metabolite of Thyroxine.
Computed Properties
Molecular Weight:650.97
XLogP3:1.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:650.7901
Monoisotopic Mass:650.7901
Topological Polar Surface Area:92.8
Heavy Atom Count:23
Complexity:402
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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