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Home > Encyclopedia > 3′,5′,3-Triiodothyronine

3′,5′,3-Triiodothyronine

3′,5′,3-Triiodothyronine structure

3′,5′,3-Triiodothyronine 

structure
  • CAS No:

    5817-39-0

  • Formula:

    C15H12I3NO4

  • Chemical Name:

    3′,5′,3-Triiodothyronine

  • Synonyms:

    L-Tyrosine,O-(4-hydroxy-3,5-diiodophenyl)-3-iodo-;Alanine,3-[4-(4-hydroxy-3,5-diiodophenoxy)-3-iodophenyl]-,L-;O-(4-Hydroxy-3,5-diiodophenyl)-3-iodo-L-tyrosine;3,3′,5′-Triiodo-L-thyronine;3,3′,5′-Triiodothyronine;rT3;Reverse T3;Reverse triiodothyronine;3′,5′,3-Triiodothyronine;Reverse L-triiodothyronine;Isoliothyronine;3,3′,5′-L-Triiodothyronine;3,3′,5′-T3;(2S)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3-iodophenyl]propanoic acid;(S)-2-Amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3-iodophenyl)propanoic acid;(S)-2-Amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3-iodophenyl)propanoicacid;2820-50-0

  • Categories:

    Active Pharmaceutical Ingredients  >  Hormones and the Endocrine System

Description

Beige Powder


3,3',5'-triiodo-L-thyronine is a 3,3',5'-triiodothyronine. It is a tautomer of a 3,3',5'-triiodo-L-thyronine zwitterion.|A metabolite of THYROXINE, formed by the peripheral enzymatic monodeiodination of T4 at the 5 position of the inner ring of the iodothyronine nucleus.

3′,5′,3-Triiodothyronine Basic Attributes

650.97

650.97

229-999-3

8NZ4Y08T96

DTXSID3046908

2922509090

Characteristics

92.8

1.7

powder

2.4±0.1 g/cm3

206 °C (decomp)

534.6°C at 760 mmHg

9℃

1.763

2-8°C

Safety Information

UN1230 - class 3 - PG 2 - Methanol, solution

3

36/37/38-20/21/22-39/23/24/25-23/24/25-11

36-45-36/37-16

AY6750000

Xn,T,F

P210-P260-P280-P301 + P310 + P330-P302 + P352 + P312-P370 + P378

H225-H301 + H311 + H331-H370

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P312, P322, P330, P363, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

3,3',5'-Triiodothyronine

3′,5′,3-Triiodothyronine Use and Manufacturing

One of the hormones produced by the thyroid gland that is involved in the maintenance of metabolic homeostasis. Also produced in peripheral tissues as the active metabolite of Thyroxine.

Computed Properties

Molecular Weight:650.97
XLogP3:1.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:650.7901
Monoisotopic Mass:650.7901
Topological Polar Surface Area:92.8
Heavy Atom Count:23
Complexity:402
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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