Tannins

1701.20000

1700.17000

215-753-2

DTXSID2026076

YELLOWISH-WHITE TO LIGHT BROWN, AMORPHOUS, BULKY POWDER OR FLAKES, OR SPONGY MASSES|PALE YELLOWISH-BROWN

3201909000

777.98000

4.83810

Tannic acid is a light yellow to tan solid with a faint odor. Sinks and mixes with water. (USCG, 1999)

2.12 g/cm3

200 °C

198ºC

1.927

H2O: 250 g/L (20 ºC)

Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed. Store protected fr

FAINT CHARACTERISTIC ODOR

ASTRINGENT TASTE

AQ SOLN DECOMP ON HEATING; REPORTED TO CATALYSE FORMATION OF NITROSODIETHYLAMINE

Water soluble. Gradually darkens on exposure to air and/or light

Esters, Sulfate Esters, Phosphate Esters, Thiophosphate Esters, and Borate Esters

TANNIC ACID decomposes at 210° C to carbon dioxide and pyrogallol, which can form irritating vapors (USCG, 1999). Incompatible with salts of heavy metals, alkaloids, gelatin, albumin, starch, oxidizing substances-e.g., permanganates, chlorates; lime water [Merck].

980 °F (USCG, 1999)|980 °F.

NONH for all modes of transport

2

R40

S24/25; S36; S26; S36/37/39; S22

WW5075000

Xi

Stable. Incompatible with metallic salts, strong oxidizing agents, iron and other heavy metals.

P273

H412

Special Hazards of Combustion Products: Decomposes at 210° to carbon dioxide and pyrogallol, which can form irritating vapors. (USCG, 1999)

|Warning|H319 (76.43%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]|P264, P273, P280, P305+P351+P338, P337+P313, and P501|Aggregated GHS information provided by 2199 companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Dust mask; goggles or face shield; protective gloves (USCG, 1999)

SLIGHT, WHEN EXPOSED TO HEAT OR FLAME. SPONTANEOUS HEATING: NO.

WATER.

APPARENTLY DIETARY TANNIC ACID & TANNINS INCR REQUIREMENT FOR METHYL GROUP DONORS.

PRACTICALLY ALL WOOD & VEGETATION CONTAIN SOME FORM OF TANNIN IN LEAVES, TWIGS, BARK, WOOD OR FRUIT. ...BARK OF OAK, EUCALYPTUS, MANGROVE, HEMLOCK, PINE & WILLOW; WOOD OF QUEBRACHO, CHESTNUT & OAK; FRUITS OF TARA, MYROBALANS & DIVI-DIVI; LEAVES OF SUMAC & GAMBIER...ROOTS OF CANAIGRE & PALMETTO.

...NATURAL OCCURRENCE IN COFFEE AND TEA.

...FORMERLY USED ORALLY FOR SYMPTOMATIC TREATMENT OF DIARRHEA, TOPICALLY FOR MANAGEMENT OF EXTENSIVE BURNS, & RECTALLY FOR RELIEF OF VARIOUS RECTAL DISORDERS. ... USE...AS CHEMICAL ANTIDOTE IN POISONING IS ONLY OF LIMITED VALUE, & SOME METALS & ALKALOIDS ARE NOT PRECIPITATED BY IT. ...FEW IF ANY LEGITIMATE MEDICAL USES...|IT OCCURS IN PRODUCTS FOR TREATMENT OF EFFECTS OF POISON-IVY & POISON-OAK & FOR OTHER SKIN APPLICATIONS.|OINTMENT OR SPRAY OF TANNIC ACID IS USED IN TREATMENT OF BED SORES, WEEPING ULCERS, ETC. TANNIC ACID GLYCERITE NF XII WAS FORMERLY USED LOCALLY FOR SORE THROAT & STOMATITIS & TO HARDEN NIPPLES DURING NURSING.|MEDICATION (VET): TOPICALLY, AS HEMOSTATIC ASTRINGENT ON MOIST ECZEMAS, GALLS, WOUNDS, & IN OTIS EXTERNA. ... USED IN REPOSITORY PARENTERAL VITAMIN B-12.|For more Therapeutic Uses (Complete) data for TANNIC ACID (6 total), please visit the HSDB record page.

...INTERFERES WITH HIGHLY EFFICIENT ADSORBENT ACTION OF ACTIVATED CHARCOAL.|...EMPLOYED IN TREATMENT OF BURNS. ... DISADVANTAGE OF TANNIC ACID IS THAT IT IS NOT ACTIVE GERMICIDE. IT IS ALSO ABSORBED FROM DENUDED SURFACES & MAY CAUSE SERIOUS SYSTEMIC TOXICITY, PARTICULARLY LIVER DAMAGE. FURTHERMORE, IT CAUSES NECROSIS OF VIABLE TISSUE IN BURNED AREA.|VET: IT IS STOMACH IRRITANT. ... WARNING: EXCESSIVE DIETARY INTAKE CAN CAUSE GROWTH DEPRESSION & TOXICITY. USE IN ENEMAS MAY BE TOXIC.

ERRATICALLY ABSORBED.|...ADMIN BY IP OR SC INJECTION TO RATS APPEARED IN LIVER 1 HR AFTER ADMIN & WAS CONCENTRATED IN NUCLEI AS EARLY AS 3 HR LATER.|...INCR CONCN OF TANNIC ACID IN BLOOD OF RABBITS & DOGS GIVEN...BY STOMACH TUBE, WITH MAX LEVEL AFTER 3 HR. ABSORPTION...FROM COLON, AS SHOWN BY RISING BLOOD LEVELS, WAS DEMONSTRATED IN RABBITS, SHEEP, GOATS, RATS & DOGS.|...SUFFICIENT TANNIC ACID MAY BE ABSORBED FROM GI TRACT, DENUDED SURFACES, & MUCOUS MEMBRANES TO CAUSE SEVERE CENTRALOBULAR NECROSIS OF LIVER.

YIELDS GALLIC ACID IN RATS; BLUMENBERG, FW, & KESSLER, FJ, ARZNEIMITTEL-FORSCH, 10, 742 (1960). /FROM TABLE/

TANNIC ACID IN TEA ACCOUNTS FOR USE OF STRONG TEA IN UNIVERSAL ANTIDOTE, PRESUMABLY FOR DUAL PURPOSE OF PRECIPITATING TOXIC ALKALOIDS & OF HARDENING SURFACE OF GI MUCOSA & ITS MUCOUS LAYER.

Inhalation causes irritation of nose and throat, coughing, and sneezing. Ingestion may cause gastric disturbance. Contact with eyes causes irritation. (USCG, 1999)

INHALATION: move to fresh air. INGESTION: give large amount of water; induce vomiting. EYES or SKIN: flush with water. (USCG, 1999)

IN AUTOPSIED HUMAN BURN CASES...OBSERVED LIVER NECROSIS ATTRIBUTABLE TO ABSORPTION OF TANNIC ACID THROUGH BURNED SKIN SURFACES.|MODERATELY TOXIC BY INGESTION & INHALATION.|GALLIC ACID DOES NOT PRODUCE LIVER DAMAGE, BUT MAY CAUSE DEATH FROM ACUTE RENAL FAILURE. THUS, HYDROLYSIS OF TANNIC ACID MAY ACCOUNT FOR HISTOLOGICAL CHANGES IN KIDNEY.|SUMMARY TOXICITY STATEMENT: ACUTE... HIGH VIA IV & SC. HIGH= CAPABLE OF CAUSING DEATH OR PERMANENT INJURY DUE TO EXPOSURES OF NORMAL USE; INCAPACITATING & POISONOUS; REQUIRES SPECIAL HANDLING.|For more Human Toxicity Excerpts (Complete) data for TANNIC ACID (6 total), please visit the HSDB record page.

Acid, Tannic

TANNIC ACID OF COMMERCE USUALLY CONTAINS ABOUT 10% WATER. ... IT IS PRODUCED FROM TURKISH OR CHINESE NUTGALL, FORMER CONTAINING 50-60%, LATTER ABOUT 70%.|TECHNICAL C.P.; N.F.; FLUFFY; F.C.C.

All other basic organic chemical manufacturing|Tannins: ACTIVE|TANNINS MAY BE DIVIDED INTO 2 GROUPS: (A) DERIV OF FLAVANOLS, SO-CALLED CONDENSED TANNINS & (B) HYDROLYZABLE TANNINS (MORE IMPORTANT GROUP) WHICH ARE ESTERS OF SUGAR, USUALLY GLUCOSE, WITH ONE OR MORE TRIHYDROXYBENZENECARBOXYLIC ACIDS.|HYDROLYZABLE TANNINS ARE SUB-DIVIDED, ON BASIS OF PHENOLIC ACIDS WHICH THEY CONTAIN, INTO TWO GROUPS, GALLOTANNINS & ELLAGITANNINS.|SPECIFICATIONS FOR...COMMERCIAL GRADE...RESIDUE AFTER IGNITION, 1% MAX; LOSS ON DRYING, 8-12%; TANNIN, 86.1%; NON-TANNIN, 4.5%; INSOL MATERIALS, 0.4%, WATER, 9.0%; TOTAL SOLIDS, 91.0%; SOL SOLIDS, 95.0%.|TERM "TANNIN" WAS INTRODUCED IN 1796 BY SEQUIN TO DENOTE SUBSTANCES WITH CAPACITY TO CONVERT ANIMAL SKIN TO LEATHER. TANNINS OF VEGETABLE ORIGIN CONSTITUTE LARGE GROUP OF PHENOLIC COMPD... VARY FROM SIMPLE PHENOLS SUCH AS GALLIC ACID TO MACROMOLECULES WITH MOLECULAR WT OF BETWEEN 500 & 3000.|For more General Manufacturing Information (Complete) data for TANNIC ACID (10 total), please visit the HSDB record page.

TITRIMETRIC METHOD: KAUSHIK, RL & PROSAD, R (1973) J IND CHEM SOC, 50, 17-18. COLORIMETRIC METHOD: WILLEMOT, J & PARPY, G (1970) ANN PHARM FRANC, 28, 391-395.|ANALYTICAL CHEMISTRY FOR CLOVES & ALLSPICE. 9.098 ANALYTICAL CHEMISTRY IN DISTILLED LIQUORS.

Food additives -> Flavoring Agents|Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients|Cosmetics -> Astringent

Flavoring Agents|Flavouring Agent -> FLAVOURING_AGENT; Food Additives -> FILTERING_AID;