Propylbenzene
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Propylbenzene
structure -
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CAS No:
103-65-1
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Formula:
C9H12
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Chemical Name:
Propylbenzene
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Synonyms:
Benzene,propyl-;Propylbenzene;Isocumene;1-Phenylpropane;n-Propylbenzene;1-Propylbenzene;NSC 16941;74296-31-4
- Categories:
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CAS No:
Description
Liquid
N-propyl benzene appears as a clear colorless liquid. Insoluble in water and less dense than water. Flash point 86°F. Mildly toxic by ingestion and inhalation. Used to make other chemicals.|Liquid
N-propyl benzene appears as a clear colorless liquid. Insoluble in water and less dense than water. Flash point 86°F. Mildly toxic by ingestion and inhalation. Used to make other chemicals.|Propylbenzene is an alkylbenzene that is benzene having one of its aromatic hydrogens substituted by a propyl group.
Propylbenzene Basic Attributes
120.19
120.19
1903006
203-132-9
0WR86ZHG2Z
16941
2364
DTXSID3042219
Colorless liquid|Liquid
29029090
Characteristics
0
3.69
Clear slightly yellow Liquid
0.8620 g/cm3 @ Temp: 20 °C
-99.5 °C
159.2 °C
118 °F
1.495
Miscible with alcohol, ether, acetone, benzene, and petroleum ether. Slightly miscible with water.
2-8°C
2 mm Hg ( 20 °C)
4.14 (vs air)
Oral-Rat LD50: 6040 mg/kg
In case of fire, high temperature, oxidant is more flammable; burning produces irritating smoke
0.8-6%(V)
6.00e-12 cm3/molecule*sec
0.01 atm-m3/mole|Henry's Law constant= 1.05X10-2 atm-cu m/mol @ 25 °C
Partition coefficients at 37 °C for N-propylbenzene into blood= 47.0; into oil= 9,780.|Hydroxyl radical rate constant= 6.1X10-12 cu cm/molecule-sec @ 25 °C
Highly flammable. Insoluble in water.
Hydrocarbons, Aromatic
Highly Flammable
Vigorous reactions, sometimes amounting to explosions, can result from the contact between aromatic hydrocarbons, such as PROPYL BENZENE, and strong oxidizing agents. They can react exothermically with bases and with diazo compounds. Substitution at the benzene nucleus occurs by halogenation (acid catalyst), nitration, sulfonation, and the Friedel-Crafts reaction.
842 °F
Lower flammable limit: 0.8% by volume; Upper flammable limit: 6.0% by volume
Safety Information
III
3
UN 2364 3/PG 3
2
10-37-51/53-65-39/23/24/25-23/24/25-11
24-37-61-62-45-36/37-16
DA8750000
Xi,N,Xn,T,F
Treasury is ventilated, low temperature and dry; stored separately from oxidant
Explosive when mixed with air
Stable. Flammable. Incompatible with strong oxidizing agents.
P261-P273-P301 + P310-P331
H226-H304-H335-H411
SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.|The following wastewater treatment technologies have been investigated for n-propyl benzene: concentration process: biological treatment.
... Can react with oxidizing materials.
Special Hazards of Combustion Products: Vapor may travel considerable distance to a source of ignition and flashback. (USCG, 1999)|Flammable - 3rd degree
|Danger|H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]|P210, P233, P240, P241, P242, P243, P261, P271, P273, P280, P301+P310, P303+P361+P353, P304+P340, P312, P331, P370+P378, P391, P403+P233, P403+P235, P405, and P501|Aggregated GHS information provided by 1256 companies from 23 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H226: Flammable liquid and vapor [Warning Flammable liquids]|Warning|P210, P233, P240, P241, P242, P243, P280, P303+P361+P353, P370+P378, P403+P235, and P501
Excerpt from ERG Guide 128 [Flammable Liquids (Water-Immiscible)]: As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions. LARGE SPILL: Consider initial downwind evacuation for at least 300 meters (1000 feet). FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)
Excerpt from ERG Guide 128 [Flammable Liquids (Water-Immiscible)]: ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. A vapor-suppressing foam may be used to reduce vapors. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. Use clean, non-sparking tools to collect absorbed material. LARGE SPILL: Dike far ahead of liquid spill for later disposal. Water spray may reduce vapor, but may not prevent ignition in closed spaces. (ERG, 2016)
Self-contained breathing apparatus, rubber boots and heavy rubber gloves. (USCG, 1999)
Flammable, moderate fire risk.|A very dangerous fire hazard when exposed to heat, flame, or oxidizers ...
LEL: 0.8%; UEL: 6%|A moderate explosion hazard in the form of vapor when exposed to heat or flame.
To fight fire, use foam, carbon dioxide, dry chemical.|If material on fire or involved in fire: Do not extinguish fire unless flow can be stopped or safely confined. Use water in flooding quantities as fog. Solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use foam, dry chemical, or carbon dioxide. Keep run-off water out of sewers and water sources.
If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Attempt to stop leak if without undue personnel hazard. Use water spray to knock-down vapors.|Personnel protection: Avoid breathing vapors. Keep upwind. ... Avoid bodily contact with the material. ... Do not handle broken packages unless wearing appropriate personal protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water. ... If contact with the material anticipated, wear appropriate chemical protective clothing.
/GUIDE 128: FLAMMABLE LIQUIDS (NON-POLAR/WATER-IMMISCIBLE)/ Fire or Explosion: HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water. Substances may be transported hot.|/GUIDE 128: FLAMMABLE LIQUIDS (NON-POLAR/WATER-IMMISCIBLE)/ Health: Inhalation or contact with material may irritate or burn skin and eyes. Fire may produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.|/GUIDE 128: FLAMMABLE LIQUIDS (NON-POLAR/WATER-IMMISCIBLE)/ Public Safety: CALL Emergency Response Telephone Number ... . As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate closed spaces before entering.|/GUIDE 128: FLAMMABLE LIQUIDS (NON-POLAR/WATER-IMMISCIBLE)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Structural firefighters' protective clothing will only provide limited protection.|For more DOT Emergency Guidelines (Complete) data for N-PROPYLBENZENE (8 total), please visit the HSDB record page.
No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./|The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.|The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.
... IRRITATING TO MUCOUS MEMBRANES, EYES, NOSE, THROAT & SKIN.
| 2 - Materials that, under emergency conditions, can cause temporary incapacitation or residual injury.| 3 - Liquids and solids that can be ignited under almost all ambient temperature conditions. Materials produce hazardous atmospheres with air under almost all ambient temperatures or, though unaffected by ambient temperatures, are readily ignited under almost all conditions.| 0 - Materials that in themselves are normally stable, even under fire conditions.
The major hazards encountered in the use and handling of n-propylbenzene stem from its toxicologic properties and flammability. Toxic by all routes (ie, inhalation, ingestion, dermal contact), exposure to this colorless liquid may occur from its use in textile dyeing and printing, as a solvent for cellulose acetate, and in the manufacture of methylstyrene. Effects from exposure may include burns to the skin and eyes, nausea, headache, dizziness, central nervous system depression, and unconsciousness. In activities and situations where over-exposure may occur, wear a positive pressure self-contained breathing apparatus and protective clothing. If contact should occur, immediately irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes, and wash exposed skin thoroughly with soap and water. Contaminated clothing should be removed and left at the site. This substance is flammable and may be ignited by heat, sparks, or flames. Its heavier-than-air vapor may travel to a source of ignition and flash back, or accumulate to explosive concentrations in enclosed spaces, such as sewers. Also, containers of n-propylbenzene may explode in the heat of a fire. For fires involving this substance, extinguish with dry chemical, CO2, water spray, fog, or alcohol-resistant foam. Isolate for 1/2 mile in all directions if tank, rail car or tank truck is involved in the fire. For small spills of n-propylbenzene, take up with sand or other noncombustible absorbent, and place into container for later disposal. Dike far ahead of large spills to contain for later disposal.
n-Propylbenzene has been qualitatively detected in various wastewaters from the following industries: petroleum refining, textile mills, auto and other laundries, plastics mfg, and publicly owned treatment works(1). Leachate from 4 hazardous waste landfills in Germany contained n-propylbenzene levels of 10-700 ug/l(3). An n-propylbenzene concn of 69 mg/cu m was detected in gas emissions from a landfill in Great Britain(4). An aqueous effluent from a US petroleum refinery had a n-propylbenzene concn of 13 ng/g(5). n-Propylbenzene is a component of leachate from a landfill in Germany, being detected up to a distance of 56 m(5). Maximum concns of n-propylbenzene in the off-gas at aerated grit chambers in two Ontario, Canada municipal wastewater treatment plants were 205 and 203 ug/l(6).|Based upon dynamometer tests, the avg n-propylbenzene emission rate from gasoline-powered engines is 1.2 mg/km(1). Emission rates for n-propylbenzene from motor vehicles was calculated to be 34 mg/l of fuel consumed based on measurements made inside and outside a Los Angeles roadway tunnel(2). It is also a component of exhaust emissions from four-stroke lawn mower engines: n-propylbenzene comprised 0.57% of total organic emissions from baseline gasoline and 0.55% of total organic emissions in reformulated gasoline(3). Four stroke outboard motors are also a source of n-propylbenzene into surface waters(4).|n-Propylbenzene has also been detected as a possible volatile (C3-benzene) from furniture coatings for wood-based materials(1) and as a volatile emission from building materials (concn): linoleum tile (2.3 ug-sq m/hr); black rubber molding (0.96 ug-sq m/hr); vinyl edge molding (0.34 ug-sq m/hr); large diameter telephone cable (0.65 ug-sq m/hr); small diameter telephone cable (0.79 ug-sq m/hr); polystyrene foam insulation (0.70 ug-sq m/hr); cove adhesive (110 ug-sq m/hr); latex caulk (2.7 ug-sq m/hr); carpet (0.49 ug-sq m/hr)(2).
n-Propylbenzene was not detected (detection limit 5-23 ppb) in sediments collected from the Duwamish River Delta (Puget Sound, WA)(1).
SOURCE DOMINATED: n-Propylbenzene was detected in tunnel air at 0.037 g/kg (traffic) and 0.052 (congested) from the Craeybeckx highway tunnel in Antwerp Belgium(1).|URBAN/SUBURBAN: An evaluated database of US air monitoring data for the years 1970-1987 contains the following data for n-propylbenzene (concn is reported as daily median conc): suburban sites-213 samples, 0.123 ppb; urban sites-520 samples, 0.167 ppb(1). Air samples collected in Tulsa, OK in Jul 1978 contained n-propylbenzene levels of 0-0.9 ppb(2); samples from Rio Blanco County, CO (Jul 1978) had levels of 0.5-1.6 ppb(2). Ambient air samples collected in Long Beach, Burbank, Azuza, Los Angeles and Inglewood, CA (date no reported) contained n-propylbenzene levels of 0.001-0.011 ppm(3). The avg concn in the ambient air of Sydney, Australia between Sep 1979 and June 1980 (140 samples) was 0.4 ppb(4). The n-propylbenzene concn in Los Angeles, CA air range from 1-3 ppb during Sep-Nov 1981 monitoring(5).|URBAN/SUBURBAN: The avg concns of n-propylbenzene in the air of Vienna, Austria during Oct 1986 to Feb 1987 monitoring were 0.6 ppb (background), 2.2 ppb (suburbs), and 4.8 ppb (streets)(1). An avg n-propylbenzene concn of 2 ppb was monitored in Los Angeles, CA air during the fall of 1966(2). Levels ranging from 0.2-61.1 ppb were detected in the ambient air of Houston, TX during 1973 and 1974 monitoring(3). Air samples from Atlanta, GA contained n-propylbenzene at a concn of <5 ppbC(4).|RURAL/REMOTE: An evaluated database of US air monitoring data for the years 1970-1987 contained the following data for n-propylbenzene (conc is reported as daily median conc): remote sites-2 samples, 0.056 ppb; rural sites-2 samples, 0.056 ppb(1). Samples from the Smokey Mountains (Sept 1978) had levels of 0-0.6 ppb(2).|INDOOR AIR: n-Propylbenzene was detected in 85% of the indoor air of 26 houses in Helsinki, Finland(1). The median concn in a normal house was 0.62 ug/cu m(1). In "sick houses", 10.5% contained n-propylbenzene at 5-10% greater than average; 2.6% houses contained 10-50% greater than average, and 2.6% houses contained 200-1000% greater than average concn of n-propylbenzene(1).
n-Propylbenzene has been qualitatively detected in latex paint(1).
Toxicity
practically nontoxic
LD50 Rat oral 6040 mg/kg
n-Propylbenzene occurs as a natural constituent in petroleum(1,3) and bituminous coal(2).
Incineration of organic, petroleum or coal wastes, and combustion of fuels will release n-propylbenzene to the atmosphere(1). General uses of asphalt and naphtha and use as a solvent will release n-propylbenzene to the environment(1). n-Propylbenzene is emitted in the exhaust from gasoline and diesel engines(2). Outboard motors and motor boats have been identified as sources of n-propylbenzene emissions to water(3,4). n-Propylbenzene can be released to the environment in leachates and vapor emissions from landfills(5,6).|n-Propylbenzene's production and use as a solvent and use in textile dyeing(1) may result in its release to the environment through various waste streams(SRC).
TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 955(SRC), determined from molecular connectivity indices(2), and measured values of 495 to 725(3,4) indicates that n-propylbenzene is expected to have low mobility in soil(SRC). Volatilization of n-propylbenzene from moist soil surfaces is expected to be an important fate process(7) given a Henry's Law constant of 1.05X10-2 atm-cu m/mole(5). The potential for volatilization of n-propylbenzene from dry soil surfaces may exist(SRC) based upon a vapor pressure of 3.42 mm Hg(6). Biodegradation from soil may occur based on results from activated sludge studies(8).|AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 955(SRC), determined from molecular connectivity indices(2), as well as measured Koc values ranging from 495 to 725(3,4), indicate that n-propylbenzene is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(5) based upon a Henry's Law constant of 1.05X01-2 atm-cu m/mole(6). Using this Henry's Law constant and an estimation method(5), volatilization half-lives for a model river and model lake are 1 hr and 4 days, respectively(SRC). Volatilization half-lives of 1.3 to 19 days have been predicted for the Narraganset Bay near RI where volatilization is expected to be the major removal process(10). Aquatic hydrolysis is not an important fate process(SRC) due to the lack of hydrolyzable functional groups(5). According to a classification scheme(7), an estimated BCF of 138(SRC), from its log Kow of 3.69(8) and a regression-derived equation(9), suggests the potential for bioconcentration in aquatic organisms is moderate. Biodegradation from water may occur based on activated sludge studies, with theoretical BODs ranging from 21.8 to 43.7%(11,12).|ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), n-propylbenzene, which has a vapor pressure of 3.42 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase n-propylbenzene is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 2 days(SRC), calculated from its rate constant of 5.0X10-12 cu cm/molecule-sec at 25 °C(3). The detection of n-propylbenzene in rainwater samples(4) suggests that physical removal from the atmosphere by wet deposition is possible(SRC).
The rate constant for the vapor-phase reaction of n-propylbenzene with photochemically-produced hydroxyl radicals is 6.0X10-12 cu cm/molecule-sec at 25 °C(1). This corresponds to an atmospheric half-life of about 2 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(2). Aquatic hydrolysis is not an important fate process(SRC) due to the lack of hydrolyzable functional groups(3). n-Propylbenzene did not directly photolyze in experiments using pure aqueous seawater solutions and simulated sunlight(4); however, addition of an anthraquinone photosensitizer resulted in n-propylbenzene degradation and a formation of 1-phenyl-1-propanone, 1-phenyl-1-propanol, and benzaldehyde(4).
An estimated BCF of 138 was calculated for n-propylbenzene(SRC), using a log Kow of 3.69(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is high.
741.31 L/kg|A Koc of 725 was measured for n-propylbenzene using a surface sediment collected from the Tamar estuary(1). A similar Koc of 676 was measured in a humic acid column via HPLC(2). Adsorption percentages ranging from 0.16 to 5.58% were measured in soil column studies using three different soil types and a sludge sample(3). Using a structure estimation method based on molecular connectivity indices(4), the Koc for n-propylbenzene can be estimated to be 955(SRC). According to a classification scheme(5), these estimated and measured Koc values suggest that n-propylbenzene is expected to have low mobility in soil.
The Henry's Law constant for n-propylbenzene is 1.05X10-2 atm-cu m/mole(1). This Henry's Law constant indicates that n-propylbenzene is expected to volatilize rapidly from water surfaces(2). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec)(2) is estimated as 1 hour(SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec)(2) is estimated as 4 days(SRC). Results of mesocosm studies simulating the Narragansett Bay indicate that volatilization is the major removal process from seawater(3); volatilization half-lives of 1.3-19 days were estimated for summer, spring and winter seasons(5). n-Propylbenzene's Henry's Law constant(1) indicates that volatilization from moist soil surfaces may occur(SRC). The potential for volatilization of n-propylbenzene from dry soil surfaces may exist(SRC) based upon it's vapor pressure of 3.42 mm Hg(4).
DRINKING WATER: Results of the USEPA Groundwater Supply Survey (finished water supplies that use groundwater sources) found that n-propylbenzene was detected in only one of 945 sources (concn of 0.98 ug/l in the one source) that were surveyed from throughout the US(1). Drinking water samples collected from Miami, FL and Cincinnati, OH during 1974 and 1975 had respective n-propylbenzene concns of 0.05 and 0.01 ug/l(2). A drinking water sample from Cincinnati, OH in Feb 1980 had a n-propylbenzene concn of 33 ng/l(3).|SURFACE WATER: The n-propylbenzene concn in Lake Constance varied from 4 to 132 ng/l; concns were observed to increase with increasing boat traffic(1). n-Propylbenzene was detected at levels up to 6 ug/l in river waters and their estuaries in Osaka City, Japan(2). During a 1992-1993 study, n-propylbenzene was not detected in surface water from a wetland in Orange County, FL which is adjacent to a landfill; it was detected in the 1989-1990 study at a concn of 0.08 ug/l(3).|GROUNDWATER: A well water sample collected near a landfill in Delaware had an n-propylbenzene concn of 0.5 ug/l(1). During a 1992-1993 study, n-propylbenzene was measured in ground water from a wetland in Orange County, FL which is adjacent to a landfill, ranging from not detected to 0.65 ug/l; it was detected in the 1989-1990 study (not detected to 0.08 ug/l)(3).|RAIN/SNOW: Trace levels (concn not reported) of n-propylbenzene were detected in rainwater collected in Los Angeles, CA on Mar 26, 1982(1).
n-Propylbenzene has been qualitatively identified as a volatile constituent of chickpea flour(1), roasted filbert nuts(2) and scrambled eggs(3). Level in peanut oil was less than 2% of the total volatiles(4).
Occupational exposure to n-propylbenzene occurs through dermal contact and inhalation of vapor(1); absorption takes place by inhalation and in small quantities through intact skin(1).|NIOSH (NOHS Survey 1972-1974) has statistically estimated that 16,823 workers are potentially exposed to n-propylbenzene in the USA(1). Mean air levels of 0.1-0.2 ppm n-propylbenzene were detected inside two US factories involved in spray painting and glueing(2). Air samples collected inside a tire re-treading factory in Italy contained n-propylbenzene levels of 0-15 ug/cu m(2); a shoe sole factory (vulcanization area) had a level of 30-300 ug/cu m(2). Occupational exposure to n-propylbenzene may occur through inhalation and dermal contact with this compound at workplaces where n-propylbenzene is produced or used. The general population is continually exposed to n-propylbenzene through inhalation since it has been detected frequently in the atmosphere(SRC).
n-Propylbenzene was qualitatively detected in 8 of 46 samples of human adipose tissue analyzed during the EPA National Human Adipose Tissue Survey in fiscal year 1982(1).
Drug Information
... PROBABLY READILY ABSORBED FROM GI TRACT & LUNG & EXCRETED MAINLY IN URINE OF HUMANS.
IN RATS, THERE APPEARS TO BE A DUAL METABOLIC PATHWAY: SIDE-CHAIN OXIDATION & RING HYDROXYLATION, WITH FORMER PREFERRED.
4.00 Days
May be harmful by inhalation, ingestion, or skin absorption. May cause eye and skin irritation. (USCG, 1999)
INHALATION: Call for medical aid. Remove the victim to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen. SKIN: Wash with soap and copious amounts of water. EYES: Flush with copious amounts of water for at least 15 minutes. (USCG, 1999)
Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal ... . /Aromatic hydrocarbons and related compounds/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious or in respiratory arrest. Positive-pressure ventilation techniques with a bag-valve-mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . Treat seizures with diazepam (Valium) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Aromatics hydrocarbons and related compounds/
... IRRITATING TO MUCOUS MEMBRANES, EYES, NOSE, THROAT & SKIN. SYSTEMICALLY, IT CAUSES DEPRESSION OF CNS, HEADACHE, ANOREXIA, MUSCULAR WEAKNESS, INCOORDINATION, NAUSEA, VERTIGO, MENTAL CONFUSION, & UNCONSCIOUSNESS.|The action of the alkylbenzenes under conditions of acute exposure resembles those of the general anesthetics. /Alkylbenzenes/
n-propylbenzene
Propylbenzene Use and Manufacturing
Prepd by the action of diethyl sulfate on benzyl magnesium chloride.|... IS PRODUCED IN PETROLEUM REFINING & AS BYPRODUCT OF CUMENE MFR.|PROBABLY BY ALKYLATION OF BENZENE WITH N-PROPYL CHLORIDE IN THE PRESENCE OF ALUMINUM CHLORIDE; FRACTIONAL DISTILLATION OF PETROLEUM REFORMATE.|Reaction of benzylmagnesium chloride and diethyl sulfate.|Petroleum refining; by-product of cumene mfg.
In textile dyeing and printing; as solvent for cellulose acetate.
Intermediates
Fuels and related products
1,000,000 - 10,000,000 lb|(1977) AT LEAST 4.54X10+10 GRAMS
All other basic organic chemical manufacturing|Benzene, propyl-: ACTIVE
A modified variant of the purge-and-trap gas chromatographic analysis of volatile organic carbon compounds in water is described. The method separated over 200 organic compounds within 40 min using flame ionization and ion trap detection and is capable of quantitation down to 5 ng/l per component. The recoveries of n-propylbenzene from water at 30 and 60 C were 84 and 99%, respectively.|EPA Method 524.2. Purge-and-Trap Gas Chromatography/Mass Spectrometry. The method is applicable for the determination of volatile aromatic compounds in water, finished drinking water, raw source water or drinking water in any treatment stage. For n-propylbenzene the method has a detection limit of 0.10 ug/l and a relative standard deviation of 5.8% ug/l with a wide bore capillary column.|EPA Method 502.2. Purge-and-Trap Capillary Column Gas Chromatography with Photoionization and Electrolytic Conductivity Detectors in Series. The method is applicable for the determination of volatile organic compounds in finished drinking water, raw source water, or drinking water in any treatment stage. For n-propylbenzene the method has a detection limit of 0.004 ug/l, a percent recovery of 103%, and a relative standard deviation of recovery of 2.0 using the photoionization detector; and a method detection limit not given ug/l, a percent recovery not given and a standard deviation not given using the electrolytic conductivity detector.|AOB Method VG-011-1. Halogenated and Aromatic Volatile Organic Compounds (VOCs) in Whole Gas Analyzed by Purge and Trap GC/ELCD/PID.|For more Analytic Laboratory Methods (Complete) data for N-PROPYLBENZENE (9 total), please visit the HSDB record page.
Fire Hazards -> Flammable - 3rd degree
Computed Properties
Molecular Weight:120.19
XLogP3:3.7
Rotatable Bond Count:2
Exact Mass:120.093900383
Monoisotopic Mass:120.093900383
Heavy Atom Count:9
Complexity:60.4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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