 Home > Encyclopedia > Prostaglandin E2

Prostaglandin E2

Prostaglandin E2 structure

CAS No:
363-24-6
Formula:
C20H32O5
Chemical Name:
Prostaglandin E2
Synonyms:
Prosta-5,13-dien-1-oic acid,11,15-dihydroxy-9-oxo-,(5Z,11α,13E,15S)-;5-Heptenoic acid,7-[3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-;5-Heptenoic acid,7-[3α-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-;(5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid;PGE2;Prostaglandin E2;U 12062;11α,15α-Dihydroxy-9-oxo-5-cis,13-trans-prostadienoic acid;(15S)-Prostaglandin E2;(-)-Prostaglandin E2;11α,15α-Dihydroxy-9-ketoprosta-5,13-dienoic acid;Dinoprostone;Prostin E2;Prepidil;l-Prostaglandin E2;l-PGE2;Minprostin E2;Prostenon;Prostenone;Cervidil;Prostin;Prostin (prostaglandin);Glandin;Prostarmon E;Cerviprost;Propess;Minprositin E2;Enzaprost E;NSC 165560;NSC 196514;Primiprost;Cerviprime;11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (5Z,11α,13E,15S);5: PN: US20150065431 SEQID: 5 claimed sequence;7-[3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-cyclopentyl]-5-heptenoic acid
Categories:
Active Pharmaceutical Ingredients > Hormones and the Endocrine System

Description

Prostaglandin E2 is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation.

Prostaglandin E2 Basic Attributes

Molecular Weight：

352.47

Exact Mass：

352.47

EC Number：

206-656-6

HScode：

29375000

Characteristics

PSA：

94.83000

XLogP3：

1.88

Appearance：

Clear yellow to amber powder

Density：

1.1±0.1 g/cm3

Melting Point：

67 °C

Boiling Point：

530.1±50.0 °C at 760 mmHg

Flash Point：

288.5±26.6 °C

Refractive Index：

1.561

Water Solubility：

H2O: insoluble ;ethanol: 1 mg/mL

Storage Conditions：

−20°C

Vapor Pressure：

0mmHg at 25°C

Specific rotation：

-85.5 º (c=1, C2H5OH)

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

60-22-61

safety instructions：

53-22-26-36/37/39-45

RTECS Number：

UK8000000

Marks：

Stability/Shelf Life：

Stable under normal temperatures and pressures. Light sensitive.

Precautionary statement(s)：

P201-P308 + P313

Hazard Statements：

H302-H360

Prostaglandin E2 Use and Manufacturing

The most common and most biologically potent of mammalian prostaglandins. Isolated from sheep prostate. Oxytocic; abortifacient.

Material

Hydrogen

2-Hydroxy-1,2,3-propanetricarboxylic acid hydrate (1:1)

Potassium chloride

Drug Function and Efficacy

Extract from the above information

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Sterile Prostaglandin E2 Solution
Specifications	1ml:2mg
Manufacturer	Kaifeng Kangnuo Pharmaceutical Co., Ltd.

Sterile Prostaglandin E2 Solution
Specifications	1ml:5mg
Manufacturer	Kaifeng Kangnuo Pharmaceutical Co., Ltd.

Dinoprostone suppository
Ingredients	Dinoprostone.
Indication	Patients who have received intravenous oxytocin should only use dinoprostone in special circumstances and with caution, because prostaglandins can enhance the efficacy of oxytocin. If the two drugs are used simultaneously or consecutively, the patient's uterine contractions should be carefully monitored to prevent the occurrence of excessive uterine contractions. It is not recommended that patients who are taking oxytocin use this product at the same time.
Specifications	10mg

See More Related Drugs

Registered Holders

TIEN (TIANJIN) PHARMACEUTICAL CO LTD

United States
Active
EUROAPI Hungary Ltd

United States
Active
協和ファーマケミカル株式会社

Japan
Active

See More Registered Holders

Recommended Suppliers of Prostaglandin E2

Hangzhou Dawn Ray Pharmaceutical Co.,Ltd Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of D-Biotin,Tobramycin base,L(-)-Carnitine base,Polymyxin B sulfate USP,Kanamycin sulfate monohydrate,Finasteride 99% USP

Prostaglandin E2

CAS No.: 363-24-6

Inquiry
HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

Prostaglandin E2

CAS No.: 363-24-6

Content: 99.00%

Inquiry
Xian ZB Biotech Co.,Ltd Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of Herb Extracts,Cosmetic raw materails,API

Supply 99% Purity Prostaglandin E2 / Pge2 / Dinoprostone / Dinoprost Powder CAS 363-24-6

CAS No.: 363-24-6

Content: 99%

Inquiry
Shanghai Lonwin Chemical Co.,Ltd Contact Supplier

CN
3 YRS

Business licensed

Trader Supplier of CHEMICALS,REAGENTS

High purity Prostaglandin E2 CAS NO.363-24-6

CAS No.: 363-24-6

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
Shandong Airuike Chemical Co., Ltd. Contact Supplier

CN
3 YRS

Business licensed

Trader Supplier of api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals,CATALYST AND AUXILIARY,FLAVORS AND FRAGRANCES,Chemical Pesticides,ADDITIVE

Dinoprostone CAS 363-24-6

CAS No.: 363-24-6

Grade: Pharmaceutical Grade

Content: 99%

Inquiry