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Hydroxyacetone

Hydroxyacetone structure

CAS No:
116-09-6
Formula:
C3H6O2
Chemical Name:
Hydroxyacetone
Synonyms:
2-Propanone,1-hydroxy-;2-Propanone,hydroxy-;1-Hydroxy-2-propanone;Acetol;Acetone alcohol;Hydroxyacetone;Methanol,acetyl-;1-Hydroxyacetone;Hydroxymethyl methyl ketone;Acetylcarbinol;Hydroxypropanone;2-Oxopropanol;α-Hydroxyacetone;Acetylmethanol;Rongal 5242;NSC 102497;1-Hydroxy-2-acetone
Categories:
Flavors and Fragrances > Synthetic Fragrances

Description

colourless to yellow liquidChEBI: A propanone that is acetone in which one of the methyl hydrogens is replaced by a hydroxy group.

Liquid|Clear colourless to yellow liquid; Pungent, sweet-caramellic, somewhat choking etheral aroma

Hydroxyacetone is a propanone that is acetone in which one of the methyl hydrogens is replaced by a hydroxy group. It has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a member of propanones, a methyl ketone, a primary alcohol and a primary alpha-hydroxy ketone. It derives from an acetone.

Hydroxyacetone Basic Attributes

Molecular Weight：

74.08

Exact Mass：

74.08

BRN：

605368

EC Number：

204-124-8

UNII：

7I7YM0835W

NSC Number：

102497

DSSTox ID：

DTXSID8051590

HScode：

29144090

Characteristics

PSA：

37.3

XLogP3：

-0.78

Appearance：

Liquid

Density：

1.059 g/cm³ @ Temp: 25 °C

Melting Point：

-17 °C

Boiling Point：

145.5 °C

Flash Point：

133 °F

Refractive Index：

n 20/D 1.425(lit.)

Water Solubility：

Miscible with water, alcohol and ether.

Storage Conditions：

2-8°C

Vapor Pressure：

1.91mmHg at 25°C

Toxicity：

Oral-Rat LD50: 2200 mg/kg

Flammability characteristics：

Flammable; decomposes by heating to release irritating fumes

OH：

3.02e-12 cm3/molecule*sec

Safety Information

Packing level：

III

Hazard category：

Transport codes：

UN 1224 3/PG 3

wgk germany：

hazard class code：

2017/10/16

safety instructions：

23-24/25-5

RTECS Number：

UC2800000

Storage features：

Warehouse ventilated, low temperature and dry

Stability/Shelf Life：

Stable. Flammable. Incompatible with strong oxidizing agents, strong acids. Protect from moisture - hygroscopic.

Precautionary statement(s)：

P210, P233, P240, P241, P242, P243, P280, P303+P361+P353, P370+P378, P403+P235, P501

Hazard Statements：

H226

GHS Classification：

|Warning|H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]|P210, P233, P240, P241, P242, P243, P280, P303+P361+P353, P370+P378, P403+P235, and P501|Aggregated GHS information provided by 220 companies from 4 notifications to the ECHA C&L Inventory.

Toxicity

Toxicity class：

moderately toxic

Drug Information

MeSH Entry Terms：

acetol

Hydroxyacetone Use and Manufacturing

Methods of Manufacturing

Potassium hydroxide, anhydrous methanol and ethyl formate were refluxed together for 2 hours to prepare a methanol solution of potassium formate. It was heated to reflux with bromoacetone and reacted for 16h. After the reaction was cooled to 0℃, the potassium bromide was filtered off and the filtrate was distilled to collect 40-43℃ (1.6kPa) fractions to obtain hydroxyacetone with a yield of 54-58%.

Uses

Reagent in organic synthesis; protecting group for the synthesis of peptides.

Manufacturing Info：

2-Propanone, 1-hydroxy-: ACTIVE

Use Classification：

Food additives -> Flavoring Agents|Flavouring Agent -> FLAVOURING_AGENT; -> JECFA Functional Classes|Flavoring Agents -> JECFA Flavorings Index

Food Additive Classes：

Flavoring Agents|Flavouring Agent -> FLAVOURING_AGENT;

Computed Properties

Molecular Weight:74.08
XLogP3:-0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:74.036779430
Monoisotopic Mass:74.036779430
Topological Polar Surface Area:37.3
Heavy Atom Count:5
Complexity:40.2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Sorbitol

Glucose

Glycerol

Propylene Glycol

Potassium formate

Potassium bromide

Recommended Suppliers of Hydroxyacetone

Greenbo Biochem Contact Supplier

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Hydroxyacetone 99% high purity certified Professional producer Greenbo

CAS No.: 116-09-6

Grade: Food Grade

Content: 99%

Inquiry
Guangzhou Yaoguang Technology Co., Ltd. Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of Custom Synthetic Chemicals,Biological Stains,Pharmaceutical Intermediates,Cosmetic Grade Chemicals,Enzyme,Nucleosides,Indicators,Speciality Chemicals,Biological Chemicals,Enzyme Substrates

Hydroxyacetone, CAS:116-09-6

Unit Price: $7-8 /KG FOB

CAS No.: 116-09-6

Grade: Chemical Grade

Content: 99%

Inquiry

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Guide of Hydroxyacetone

Description
Basic Attributes
Characteristics
Safety Information
Toxicity
Drug Information
Use and Manufacturing
Computed Properties
Material
Recommended Suppliers
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