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    Home > Chemical Pesticides > Germicide > Propylene Glycol
    Propylene Glycol structure

    Propylene Glycol

    • CAS No:

      57-55-6

    • Formula:

      C3H8O2

    • Synonyms:

      1,2-Propanediol

    • China Export:

      From 2018.11 to 2019.11, total export volume of Propylene Glycol from China was 258,934,868KG while total export value was $303,077,640. The biggest proportion of exporting volume in the last 12 months was 10.99% in 2019.02.

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    Description

    (±)-1,2-Propanediol is an aliphatic alcohol and frequently used as an excipient in many drug formulations to increase the solubility and stability of drugs.

    Basic Attributes

    • 57-55-6

    • C3H8O2

    • 76.09440

    • 76.05240

    • 40.46000

    • -0.9

    • 939-872-0

    • DNIAPMSPPWPWGF-UHFFFAOYSA-N

    • 2

    • 2

    • 1.00

    • 1

    Characteristics

    • Clear viscous liquid

    • 1.036 g/mL at 25ºC(lit.)

    • -60ºC

    • 187ºC

    • 99ºC

    • n20/D 1.432(lit.)

    • Solubility in water: miscible

    • Store at RT.

    • Vapour pressure, Pa at 20°C: 10.6

    • 2.62

    • At cool temperatures, propylene glycol is stable in a well-closed container, but at high temperatures, in the open, it tends to oxidize, giving rise to products such as propionaldehyde, lactic acid, pyruvic acid, and acetic acid. Propylene glycol is chemically stable when mixed with ethanol (95%), glycerin, or water; aqueous solutions may be sterilized by autoclaving.

    Safety Information

    • 2905320000

    • NONH for all modes of transport

    • 1

    • S24/25

    • TY2000000

    • Separated from strong oxidants and alkalis. Dry. Well closed. Ventilation along the floor.

    • P264, P270, P273, P280, P301+P312, P305+P351+P338, P330, P337+P313, P391, P501

    • H302

    • Lower flammable limit: 2.6% by volume; Upper flammable limit: 12.5% by volume

    • Explosive limits , vol% in air: 2.6-12.6

    • LD50 orally in Rabbit: 19400 - 36000 mg/kg LD50 dermal Rabbit 20800 mg/kg

    Product Usage

    Propylene glycol has good solubility and less toxicity and irritation, and is widely used as solvents, extraction solvents and preservatives for injections (eg. intramuscular injections, intravenous injections) and non-injectable pharmaceutical preparations (such as oral liquid, ophthalmic preparations, otic preparations, dental preparations, rectovaginal preparations, transdermal preparations, etc.). It is better than glycerol solvent and can dissolve many substances such as corticosteroids (sex hormone), chloramphenicol, sulfonamides, barbiturate, reserpine, quinidine, corticosterone acetate, tetrahydropalmatine sulfate, mechlorethamine hydrochloride, vitamin A, vitamin D, many volatile oils, most of the alkaloids and many local anesthetics. Propylene glycol is similar to ethanol when used as a bacteriostatic agent, and its efficacy to inhibit mold is similar to glycerin and is slightly lower than that of ethanol. Propylene glycol is commonly used as a plasticizer for the aqueous film coating materials. Its mixture with equal amounts of water can delay the hydrolysis of certain drugs, and increase the stability of the preparation product. It is used as an antimicrobial preservative in 15% to 30% propylene glycol solution and semi-solid formulation, as humectants in about 15% propylene glycol topical formulation, and as solvent and co-solvent in 10% to 30% propylene glycol aerosol solvent, 10% to 25 % propylene glycol oral solution, 10% to 60% injectable formulation and 5% to 80% topical formulation.

    China Propylene Glycol Export Data

    Data referenced from General Administration of Customs,P.R.China

    2018.11-2019.11 China - America  Propylene Glycol Export Data

    From 2018.11 to 2019.11, total export volume of Propylene Glycol from China to America was 1,270,436KG while total export value was $1,652,838. The biggest proportion of exporting volume in the last 12 months was 19.90% in 2019.01.

    2018.11-2019.11 China Propylene Glycol Export Data

    From 2018.11 to 2019.11, total export volume of Propylene Glycol from China was 258,934,868KG while total export value was $303,077,640. The biggest proportion of exporting volume in the last 12 months was 10.99% in 2019.02.

    2018.11-2019.11 TOP10 Purchasing Countries' Export Data of Chinese Propylene Glycol

    From 2018.11 to 2019.11, China has exported Propylene Glycol to 110 countries in total. Country ranks by import volume from high to low is Russia, India, Turkey, Iran, Japan, Indonesia, South Africa, Egypt, Australia, Spain. The highest export volume was China to Russia, accounting for 6.62% of the total volume of China.

    Check Export Data for More Purchasing Countries

    Purchasing Country Export Volume(KG) Export Percentage Export Value($)

    Russia

    31,143,492

    6.62%

    34,222,672

    India

    27,561,612

    5.86%

    30,900,705

    Turkey

    16,784,160

    3.57%

    17,957,081

    Iran

    15,531,679

    3.30%

    21,408,647

    Japan

    13,973,698

    2.97%

    16,583,804

    Indonesia

    13,368,999

    2.84%

    15,063,853

    South Africa

    8,603,673

    1.83%

    10,333,879

    Egypt

    8,447,000

    1.80%

    10,118,931

    Australia

    7,923,291

    1.68%

    9,245,003

    Spain

    7,809,470

    1.66%

    9,104,990

    Pakistan

    5,760,270

    1.22%

    6,995,222

    Ukraine

    5,749,440

    1.22%

    6,346,380

    Poland

    5,719,009

    1.22%

    6,239,740

    Argentina

    5,265,270

    1.12%

    6,023,462

    Peru

    4,959,200

    1.05%

    6,075,424

    Canada

    4,830,420

    1.03%

    5,787,995

    Korea

    4,770,893

    1.01%

    5,839,490

    Vietnam

    4,765,680

    1.01%

    5,799,045

    Israel

    4,099,980

    0.87%

    4,647,670

    Brazil

    4,062,408

    0.86%

    4,711,655

    Saudi Arabia

    3,945,263

    0.84%

    4,459,983

    United Arab Emirates

    3,618,097

    0.77%

    3,940,615

    Chile

    3,187,560

    0.68%

    3,733,117

    Colombia

    3,095,580

    0.66%

    3,610,510

    New Zealand

    2,984,758

    0.63%

    3,935,266

    Italy

    2,374,000

    0.50%

    2,673,091

    Thailand

    2,366,837

    0.50%

    2,642,150

    Malaysia

    2,254,262

    0.48%

    2,717,592

    Ecuador

    2,185,105

    0.46%

    2,591,241

    Singapore

    2,184,381

    0.46%

    2,410,409

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