2,2′-Methylenebis[4-methyl-6-tert-butylphenol]

340.5

340.50

204-327-1

KVM0X4X57B

7781

DTXSID4020870

Off-white powder

29072900

40.5

7.2

DryPowder; DryPowder, OtherSolid

107-110 g/cm³

118-128 °C

187℃

195°C(383°F)

1.4480 (estimate)

0.007mg/l practically insoluble

Store below +30°C.

<1 hPa

LD50 orally in Rabbit: 4880 mg/kg LD50 dermal Rabbit > 2000 mg/kg

NONH for all modes of transport

1

36-62-53

26-36-60-36/37

PA3500000

Xi,Xn

Stable at normal tempertures and pressures.

P281

H361f-H413

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

|Warning|H361 (80.86%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]|P201, P202, P273, P281, P308+P313, P405, and P501|Aggregated GHS information provided by 800 companies from 29 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|Danger|H360F: May damage fertility [Danger Reproductive toxicity]|P201, P202, P281, P308+P313, P405, and P501

A sample extract of short-pile commercial grade carpet with fiber grid backings and a layer of stiff plastic glued to the backing contained a minor amount of bis(2-hydroxy-3-tert-butyl-5-methylphenyl)methane(1).

WHEN ADDED TO THE DIET FOR 4 MONTHS BEFORE TOPICAL APPLICATION OF BENZO[A]PYRENE & THEN UNTIL DEVELOPMENT OF MALIGNANCY BY THE INDUCED PAPILLOMAS, EXTRACTS FROM POLYETHYENE OR POLYPROPYLENE PRODUCTS, CONTAINING LOW AMOUNTS OF BIS(2-HYDROXY-3-TERT-BUTYL-5- METHYLPHENYL)METHANE, HAD AN INHIBITORY EFFECT ON THE CARCINOGENIC PROCESS.

LD50 MOUSE ORAL 11000 MG/KG|LD50 RAT ACUTE 5000 MG/KG

Bis(2-hydroxy-3-tert-butyl-5-methylphenyl)methane's production and use as a stabilizer used in styrenic and olefin polymers and polyoxymethylene homo and copolymers(1), and as an antioxidant(2) may result in its release to the environment through various waste streams(SRC).

TERRESTRIAL FATE: Based on a recommended classification scheme(1), an estimated Koc value of 59800(SRC), determined from an experimental log Kow(2) and a recommended regression-derived equation(3), indicates that bis(2-hydroxy-3-tert-butyl-5-methylphenyl)methane will have no mobility in soil(SRC). Volatilization of bis(2-hydroxy-3-tert-butyl-5-methylphenyl)methane may not be important from moist soil surfaces(SRC) given an estimated Henry's Law constant of 7.9X10-12 atm-cu m/mole(4,SRC), or from dry soil surfaces(SRC) based on an estimated vapor pressure of 2.5X10-9 mm Hg(5,SRC). Based on a MITI biodegradation test, bis(2-hydroxy-3-tert-butyl-5-methylphenyl)methane will not biodegrade in soil(2).|AQUATIC FATE: Based on a recommended classification scheme(1), an estimated Koc value of 59800(SRC), determined from an experimental log Kow(2) and a recommended regression-derived equation(3), indicates that bis(2-hydroxy-3-tert-butyl-5-methylphenyl)methane will adsorb to suspended solids and sediment(SRC) in the water. Bis(2-hydroxy-3-tert-butyl-5-methylphenyl)methane should not volatilize from water surfaces based on an estimated Henry's Law constant of 7.9X10-12 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). Experimental BCF values of 23-37 and 60-125 at 1 and 0.1 mg/L(2), suggest that bis(2-hydroxy-3-tert-butyl-5-methylphenyl)methane will bioconcentrate in aquatic organisms(SRC) according to a recommended classification scheme(5). Based on a MITI biodegradation test, bis(2-hydroxy-3-tert-butyl-5-methylphenyl)methane will not biodegrade in water(2).|ATMOSPHERIC FATE: According to a suggested classification scheme(1), an estimated vapor pressure of 2.5X10-9 mm Hg at 25 °C(2,SRC) indicates that bis(2-hydroxy-3-tert-butyl-5-methylphenyl)methane will exist in the particulate phase in the ambient atmosphere. Particulate-phase bis(2-hydroxy-3-tert-butyl-5-methylphenyl)methane may be physically removed from the air by wet and dry deposition(SRC).

549.54|An estimated BCF value of 33100 was calculated for bis(2-hydroxy-3-tert-butyl-5-methylphenyl)methane(SRC), using an experimental log Kow of 6.25(1) and a recommended regression-derived equation(2). Bioconcentration factors of 23-37 and 60-125 were obtained during an 8 week bioconcentration study using carp and bis(2-hydroxy-3-tert-butyl-5-methylphenyl)methane concentrations of 1 and 0.1 mg/l, respectively(1). According to a recommended classification scheme(3), the experimental BCF values suggest that bioconcentration in aquatic organisms will be moderate to high(SRC).

The Koc of bis(2-hydroxy-3-tert-butyl-5-methylphenyl)methane is estimated as approximately 59800(SRC), using an experimental log Kow of 6.25(1) and a regression-derived equation(2,SRC). According to a recommended classification scheme(3), this estimated Koc value suggests that bis(2-hydroxy-3-tert-butyl-5-methylphenyl)methane will be immobile in soil and strongly adsorbed to suspended solids and sediment in water(SRC).

The Henry's Law constant for bis(2-hydroxy-3-tert-butyl-5-methylphenyl)methane is estimated as 7.9X10-12 atm-cu m/mole(SRC) using a fragment constant estimation method(1). This value indicates that bis(2-hydroxy-3-tert-butyl-5-methylphenyl)methane will be essentially nonvolatile from water surfaces(2,SRC). Bis(2-hydroxy-3-tert-butyl-5-methylphenyl)methane's vapor pressure, 2.5X10-9 mm Hg(3,SRC) and Henry's Law constant(1,SRC) indicate that volatilization from dry and moist soil should not occur(SRC).

Bis(2-hydroxy-3-tert-butyl-5-methylphenyl)methane has been qualitatively identified in drinking water from Cincinnati, OH on 1/14/80(1).

Bis(2-hydroxy-3-tert-butyl-5-methylphenyl)methane has been qualitatively detected in two samples of human adipose tissue from a 45 and over age group in the Western Region(1).

1.07 Days

2,2'-methylenebis(4-methyl-6-tert-butylphenol)

Solid form

Adhesive manufacturing|Phenol, 2,2'-methylenebis[6-(1,1-dimethylethyl)-4-methyl-: ACTIVE

Cosmetics -> Antioxidant