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4-Bromo-2-chlorophenol

4-Bromo-2-chlorophenol structure

CAS No:
3964-56-5
Formula:
C6H4BrClO
Chemical Name:
4-Bromo-2-chlorophenol
Synonyms:
Phenol,4-bromo-2-chloro-;4-Bromo-2-chlorophenol;2-Chloro-4-bromophenol
Categories:
Agrochemicals > Pesticide Intermediates

Description

white to off-white low melting mass or crystalline

4-bromo-2-chlorophenol is a halophenol that is phenol in which the hydrogens at positions 2 and 4 have been replaced by chlorine and bromine, respectively. It is a halophenol, a member of monochlorobenzenes and an organobromine compound.

4-Bromo-2-chlorophenol Basic Attributes

Molecular Weight：

207.45

Exact Mass：

207.45

BRN：

2042867

EC Number：

223-572-5

UNII：

994SJ34D8P

DSSTox ID：

DTXSID30192745

HScode：

2908199090

Characteristics

PSA：

20.2

XLogP3：

3.1

Appearance：

White to off-white Low Melting Mass or Crystalline Needles, Powder and Chunks

Density：

1.8±0.1 g/cm3

Melting Point：

50.5 °C

Boiling Point：

233.5 °C

Flash Point：

>230 °F

Refractive Index：

1.619

Safety Information

Packing level：

I; II; III

Hazard category：

IRRITANT

Transport codes：

UN 3077 9/PG 3

wgk germany：

hazard class code：

36/37/38

safety instructions：

26-37/39-24/25

Marks：

Hazard note：

Irritant

Precautionary statement(s)：

P261-P305 + P351 + P338

Hazard Statements：

H315-H319-H335

GHS Classification：

|Warning|H315 (99.26%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 135 companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH Entry Terms：

4-bromo-2-chlorophenol

4-Bromo-2-chlorophenol Use and Manufacturing

Methods of Manufacturing

The preparation method is to obtain 2-chloro-4-bromophenol by bromination of o-chlorophenol. The o-chlorophenol and solvent are quantitatively pumped into the enamel reactor, under the conditions of stirring, negative pressure, and cooling, a certain amount of bromine is slowly added dropwise into the kettle, and the temperature is controlled at 8-12°C. After the bromine addition is completed, Continue the reaction at room temperature for 2 hours, and then maintain it at room temperature. Slowly add a quantitative 30% lye to neutralize the reactants. After stirring for 0.5 hours, the materials are pumped to the layerer and left for more than 4 hours. The lower layer is 55%～60. % 2-chloro-4-bromophenol sodium aqueous solution, acidified to obtain 2-chloro-4-bromophenol.

Uses

Used as an intermediate for pesticide propofol, but also for other organic synthesis

Computed Properties

Molecular Weight:207.45
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Exact Mass:205.91341
Monoisotopic Mass:205.91341
Topological Polar Surface Area:20.2
Heavy Atom Count:9
Complexity:99.1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Phenol

Acetic acid

Recommended Suppliers of 4-Bromo-2-chlorophenol

Shaanxi Dideu Medichem Co. Ltd Contact Supplier

CN
4 YRS

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4-Bromo-2-chlorophenol -a

CAS No.: 3964-56-5

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HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

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Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

4-Bromo-2-chlorophenol

CAS No.: 3964-56-5

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