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Triprolidine

Triprolidine structure

CAS No:
486-12-4
Formula:
C19H22N2
Chemical Name:
Triprolidine
Synonyms:
Pyridine,2-[(1E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propen-1-yl]-;Pyridine,2-[3-(1-pyrrolidinyl)-1-p-tolylpropenyl]-,(E)-;Pyridine,2-[1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]-,(E)-;Pyridine,2-[(1E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]-;2-[(1E)-1-(4-Methylphenyl)-3-(1-pyrrolidinyl)-1-propen-1-yl]pyridine;Tripyrolidine;Triprolidine;trans-2-[3-(1-Pyrrolidinyl)-1-p-tolypropenyl]pyridine;trans-1-(2-Pyridyl)-3-pyrrolidino-1-p-tolylprop-1-ene;trans-1-(4-Methylphenyl)-1-(2-pyridyl)-3-pyrrolidinoprop-1-ene;Triprolidin
Categories:
Active Pharmaceutical Ingredients > Antiallergic Drugs

Description

ChEBI: An N-alkylpyrrolidine that is acrivastine in which the pyridine ring is lacking the propenoic acid substituent. It is a sedating antihistamine that is used (generally as the monohydrochloride monohydrate) for the relief of the symptoms o uticaria, rhinitis, and various pruritic skin disorders.

Triprolidine Basic Attributes

Molecular Weight：

278.39

Exact Mass：

278.39

EC Number：

207-627-0

Characteristics

PSA：

16.1

XLogP3：

Appearance：

Solid

Density：

1.061 g/cm3

Melting Point：

59-61 °C

Boiling Point：

435.4ºC at 760 mmHg

Flash Point：

217.1ºC

Water Solubility：

5.37e-02 g/L

Vapor Pressure：

6.16E-09mmHg at 25°C

Safety Information

safety instructions：

S36/37

Triprolidine Use and Manufacturing

Antihistaminic.