 Home > Encyclopedia > 2-Isopropoxyphenol

2-Isopropoxyphenol

2-Isopropoxyphenol structure

CAS No:
4812-20-8
Formula:
C9H12O2
Chemical Name:
2-Isopropoxyphenol
Synonyms:
Phenol,2-(1-methylethoxy)-;Phenol,o-isopropoxy-;2-(1-Methylethoxy)phenol;o-Isopropoxyphenol;2-Isopropoxyphenol;Catechol monoisopropyl ether;2-Isopropyloxyphenol;1-Hydroxy-2-isopropoxybenzene;ortho-Isopropoxyphenol;2-IPP;2-(Propan-2-yloxy)phenol;2-(2-Propoxy)phenol
Categories:
Agrochemicals > Pesticide Intermediates

Request for Quotation

Description

clear light yellow to light red-brown liquid

Solid

2-isopropoxyphenol is a member of phenols and an aromatic ether.

2-Isopropoxyphenol Basic Attributes

Molecular Weight：

152.19

Exact Mass：

152.19

BRN：

1937063

EC Number：

225-379-1

UNII：

X51P4UE6X7

DSSTox ID：

DTXSID5041431

HScode：

29095090

Characteristics

PSA：

29.5

XLogP3：

2.1

Appearance：

Clear light yellow to light red-brown Liquid

Density：

1.0±0.1 g/cm3

Melting Point：

206 - 207ºC

Boiling Point：

100-102 °C

Flash Point：

190 °F

Refractive Index：

1.518

Water Solubility：

soluble in water.

Storage Conditions：

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Safety Information

wgk germany：

hazard class code：

36/37/38

safety instructions：

26-36/37/39-37/39-36

Marks：

Precautionary statement(s)：

P261-P305 + P351 + P338

Hazard Statements：

H315-H319-H335

GHS Classification：

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 42 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH Entry Terms：

2-isopropoxyphenol

2-Isopropoxyphenol Use and Manufacturing

Methods of Manufacturing

2-Isopropoxyphenol is produced by the reaction of catechol and isopropyl bromide. Slowly add isopropyl bromide dropwise to the refluxing mixture of catechol, potassium carbonate, butanone and phase transfer catalyst, continue to reflux for a certain period of time, and then distill out most of butanone (85%), Add enough water to dissolve the solid salt, and then extract with benzene. The extract is extracted with dilute sodium hydroxide solution. The extract is neutralized with dilute hydrochloric acid and then extracted with benzene, dried with calcium chloride, and most of the benzene is evaporated. Distillation under reduced pressure, collecting 100-102°C/1.46kPa fractions, yield>60% (reflux 32h yield>60%, reflux 8h yield 54%). If isopropyl chloride is used instead of isopropyl bromide, the cost can be reduced, but the process requires autoclave reaction. The domestic o-isopropoxyphenol uses the process of isopropyl chloride and catechol.

Uses

2-Isopropoxyphenol, also known as 2-(1-methylethoxy)phenol, is an important intermediate for the synthesis of carbamate pesticides.

Manufacturing Info：

Phenol, 2-(1-methylethoxy)-: ACTIVE

Computed Properties

Molecular Weight:152.19
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:152.083729621
Monoisotopic Mass:152.083729621
Topological Polar Surface Area:29.5
Heavy Atom Count:11
Complexity:112
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Catechol

Potassium carbonate

Recommended Suppliers of 2-Isopropoxyphenol

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

2-Isopropoxyphenol

CAS No.: 4812-20-8

Content: 99.00%

Inquiry
Hangzhou Chungyo Chemicals Co., Ltd. Contact Supplier

CN
3 YRS

Business licensed Certified factory

Manufactory Supplier of Dyes,Textile agent,Medical intermediate,API,Pigments,Basic Chemicals

2-Isopropoxyphenol

CAS No.: 4812-20-8

Grade: pharmaceutical grade

Content: 98%

Inquiry