D-Arginine
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D-Arginine
structure -
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CAS No:
157-06-2
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Formula:
C6H14N4O2
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Chemical Name:
D-Arginine
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Synonyms:
D-Arginine;Arginine,D-;(R)-Arginine;(2R)-2-Amino-5-(diaminomethylideneamino)pentanoic acid;(R)-2-Amino-5-guanidinopentanoic acid;(2R)-2-Amino-5-carbamimidamidopentanoic acid;(2R)-2-Amino-5-[(diaminomethylidene)amino]pentanoic acid;134309-35-6
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CAS No:
Description
white to light yellow crystal powdeChEBI: A D-alpha-amino acid that is the D-isomer of arginine.D-arginine is the D-form of arginine, which is a kind of amino acids. It can be reacted with hydrogen peroxide for non-enzymatic synthesis of nitric oxide. It has certain pharmacological activities. For example, its derivative, 1-deamino-8-D-arginine vasopressin is useful for the management of haemophilia and von Willebrand’s disease. It also has the potential to inhibit the proliferation of certain
Solid
D-arginine is a D-alpha-amino acid that is the D-isomer of arginine. It has a role as an EC 4.1.1.19 (arginine decarboxylase) inhibitor and a mouse metabolite. It is a D-alpha-amino acid and an arginine. It is a conjugate base of a D-argininium(1+). It is a conjugate acid of a D-argininate. It is an enantiomer of a L-arginine.|A D-α-amino acid that is the D-isomer of arginine (only the L-form is physiologically active).
Characteristics
125.22000
-4.2
Solid
1.46 g/cm3
238 °C
409.1ºC at 760 mmHg
201.2ºC
-23 ° (C=8, 6mol/L HCl)
1e+006 mg/L @ 25 °C (est)
Store at 0-5ºC
Safety Information
IRRITANT
NONH for all modes of transport
3
R36
S26
CF1934220
Xi
P305 + P351 + P338
H319
D-Arginine Use and Manufacturing
Arginine (abbreviated as Arg or R) encoded by the codons CGU, CGC, CGA, CGG, AGA, and AGG is an α-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH3+ form under biological conditions), an α-carboxylic acid group (which is in the deprotonated −COO− form under biological conditions), and a side chain of a 3-carbon aliphatic straight chain capped by a complex guanidinium, classifying it as a charged (at physiological pH), aliphatic amino acid. Arginine is classified as a semiessential or conditionally essential amino acid, depending on the developmental stage and health status of the individual. Preterm infants are unable to synthesize or create arginine internally, making the amino acid nutritionally essential for them. Most healthy people do not need to supplement with arginine because their body produces sufficient amounts. Arginine was first isolated from a lupin seedling extract in 1886 by the German chemist Ernst Schultze.
D-Arginine: ACTIVE
Computed Properties
Molecular Weight:174.20
XLogP3:-4.2
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:174.11167570
Monoisotopic Mass:174.11167570
Topological Polar Surface Area:128
Heavy Atom Count:12
Complexity:176
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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