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L-(+)-threo-Chloramphenicol

L-(+)-threo-Chloramphenicol structure

CAS No:
134-90-7
Formula:
C11H12Cl2N2O5
Chemical Name:
L-(+)-threo-Chloramphenicol
Synonyms:
Acetamide,2,2-dichloro-N-[(1S,2S)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-;Acetamide,2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]-,L-threo-(+)-;Acetamide,2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-,[S-(R*,R*)]-;Acetamide,2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]-,L-threo-;2,2-Dichloro-N-[(1S,2S)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide;L-threo-Chloramphenicol;L-(+)-threo-Chloramphenicol;L-threo-N-Dichloracetyl-1-p-nitrophenyl-2-amino-1,3-propanediol;Dextromycetin;L-threo-N-Dichloroacetyl-1-p-nitrophenyl-2-amino-1,3-propanediol;L-threo-(1S,2S)-1-p-Nitrophenyl-2-dichloroacetamido-1,3-propanediol;L-threo-Chloroamphenicol;Dextramycin;(+)-Chloramphenicol;(1S,2S)-2-(2,2-Dichloroacetamido)-1-(4-nitrophenyl)-1,3-propanediol;137731-89-6;13171-08-9
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Pharmaceutical Intermediates > Bulk Drug Intermediates

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L-(+)-threo-Chloramphenicol Basic Attributes

Molecular Weight：

323.12938

Exact Mass：

323.13

EC Number：

205-161-2

UNII：

U0PWV2Z3IW

DSSTox ID：

DTXSID40158453

Characteristics

PSA：

115

XLogP3：

1.1

Density：

1.2886 (rough estimate)

Melting Point：

150-151 °C

Boiling Point：

527.51°C (rough estimate)

Refractive Index：

1.6300 (estimate)

Drug Information

MeSH Entry Terms：

dextramycine

L-(+)-threo-Chloramphenicol Use and Manufacturing

The S,S-stereoisomer of Chloramphenicol (C325030). Broad spectrum antibiotic obtained from cultures of the soil bacterium Streptomyces venezuelae. It has a broad spectrum of activity against Gram-positive and gram-negative bacteria. Antibacterial; antirickettsial.

Computed Properties

Molecular Weight:323.13
XLogP3:1.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:322.0123269
Monoisotopic Mass:322.0123269
Topological Polar Surface Area:115
Heavy Atom Count:20
Complexity:342
Defined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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CAS No.: 134-90-7

Grade: Industrial Grade

Content: 99%

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Guide of L-(+)-threo-Chloramphenicol

Basic Attributes
Characteristics
Drug Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
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L-(+)-threo-Chloramphenicol

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