1,3-Dichloropropane

112.99

112.99

205-531-3

AJ1HQ2GUCP

0724

6204

1993|1992

DTXSID6022004

Colorless liquid

29031990

0

2.0

Clear colorless Liquid

1.1876 g/cm³ @ Temp: 20 °C

-99.5 °C

120.4 °C @ Press: 760 Torr

90 °F

n 20/D 1.448(lit.)

H2O: 0.8 g/L (20 ºC)

Refrigerator

Vapour pressure, kPa at 20°C: 2.4

Relative vapour density (air = 1): 3.9

Oral-Dog LDL0: 3000 mg/kg

In case of open flame, high temperature, oxidant is more flammable; heated to decompose toxic phosgene; burning produces toxic chloride fumes

Explosive limits , vol% in air: see Notes

Sweet

7.80e-13 cm3/molecule*sec

9.76e-04 atm-m3/mole|Henry's Law constant = 9.76X10-4 atm-cu m/mole @ 25 °C

Hydroxyl radical reaction rate constant = 7.80X10-13 cu cm/molecule-sec @ 25 °C

Highly flammable.

Halogenated Organic Compounds

Highly Flammable

Halogenated aliphatic compounds, such as 1,3-DICHLOROPROPANE, are moderately or very reactive. Halogenated organics generally become less reactive as more of their hydrogen atoms are replaced with halogen atoms. Low molecular weight haloalkanes are highly flammable and can react with some metals to form dangerous products. Materials in this group are incompatible with strong oxidizing and reducing agents. Also, they are incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.

-3709 cal/g

Flammable limits in air= 3.4% - 14.5% (est)

The vapour is heavier than air and may travel along the ground; distant ignition possible.

At boiling point 71.71 cal/g

Critical pressure: 41.75 atm

II

3

UN 1993 3/PG 2

2

11-20-20/22-52/53-36/37/38-39/23/24/25-23/24/25-36-20/21/22

9-16-29-33-24-61-26-45-36/37-7

TX9660000

F,Xn,T,Xi

Treasury is ventilated, low temperature and dry; stored separately from oxidant

Stable under normal temperatures and pressures.

P261-P305 + P351 + P338

H226-H315-H319-H335

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

TSCA CHIPs present a preliminary assessment of 1,3-dichloropropane's potential for injury to human health & the environment (available at EPA's TSCA Assistance Office: (202) 554-1404

Special Hazards of Combustion Products: Emits fumes of phosgene. Behavior in Fire: Reacts vigorously. (USCG, 1999)|Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire. Above 16 °C explosive vapour/air mixtures may be formed.

|Danger|H225 (81.25%): Highly Flammable liquid and vapor [Danger Flammable liquids]|P210, P233, P240, P241, P242, P243, P261, P264, P271, P273, P280, P302+P352, P303+P361+P353, P304+P312, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P370+P378, P403+P235, and P501|Aggregated GHS information provided by 33 companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H225: Highly Flammable liquid and vapor [Danger Flammable liquids]|P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P272, P280, P302+P352, P303+P361+P353, P304+P340, P309+P311, P312, P321, P332+P313, P333+P313, P362, P363, P370+P378, P403+P233, P403+P235, P405, and P501

Excerpt from ERG Guide 128 [Flammable Liquids (Water-Immiscible)]: As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions. LARGE SPILL: Consider initial downwind evacuation for at least 300 meters (1000 feet). FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)

Excerpt from ERG Guide 128 [Flammable Liquids (Water-Immiscible)]: ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. A vapor-suppressing foam may be used to reduce vapors. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. Use clean, non-sparking tools to collect absorbed material. LARGE SPILL: Dike far ahead of liquid spill for later disposal. Water spray may reduce vapor, but may not prevent ignition in closed spaces. (ERG, 2016)

Rubber gloves, self-contained breathing apparatus, coveralls or laboratory coat. (USCG, 1999)|Breakthrough times for dichloropropane on chlorinated polyethylene are less (usually significantly) than one hour as reported by two or more testers. /Dichloropropane/|Rubber gloves, self-contained breathing apparatus, protective coveralls, or laboratory coat.

Flammable|A very dangerous fire hazard when exposed to heat or flame.

Vapor may explode if ignited in an enclosed area.|Explosive limits , vol% in air:

Flash back along vapor trail may occur.

SRP: Contaminated protective clothing should be segregated in such a manner so that there is no direct personal contact by personnel who handle, dispose, or clean the clothing. Quality assurance to ascertain the completeness of the cleaning procedures should be implemented before the decontaminated protective clothing is returned for reuse by the workers. Contaminated clothing should not be taken home at end of shift, but should remain at employee's place of work for cleaning.|SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

/GUIDE 130: FLAMMABLE LIQUIDS (NON-POLAR/WATER-IMMISCIBLE/NOXIOUS)/ Fire or Explosion: HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Those substances designated with a "P" may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water. /Dichloropropane/|/GUIDE 130: FLAMMABLE LIQUIDS (NON-POLAR/WATER-IMMISCIBLE/NOXIOUS)/ Health: May cause toxic effects if inhaled or absorbed through skin. Inhalation or contact with material may irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution. /Dichloropropane/|/GUIDE 130: FLAMMABLE LIQUIDS (NON-POLAR/WATER-IMMISCIBLE/NOXIOUS)/ Public Safety: CALL Emergency Response Telephone Number ... . As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate closed spaces before entering. /Dichloropropane/|/GUIDE 130: FLAMMABLE LIQUIDS (NON-POLAR/WATER-IMMISCIBLE/NOXIOUS)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Structural firefighters' protective clothing will only provide limited protection. /Dichloropropane/|For more DOT Emergency Guidelines (Complete) data for 1,3-DICHLOROPROPANE (8 total), please visit the HSDB record page.

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./|The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

Vapor is irritating to eyes, nose, & throat. Liquid is irritating to skin & eyes.

Evacuate danger area! Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer. Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance.

Separated from food and feedstuffs, oxidants, acids, bases and alumina. Cool. Well closed. Keep in a well-ventilated room.

No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.

The substance is irritating to the eyes, skin and respiratory tract.

NO open flames, NO sparks and NO smoking. Above 16 °C use a closed system, ventilation and explosion-proof electrical equipment.

PREVENT GENERATION OF MISTS!

Use ventilation, local exhaust or breathing protection.

Protective gloves.

Wear safety spectacles.

Persons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately, when there is a release of this designated hazardous substance, in an amount equal to or greater than its reportable quantity of 1,000 lb or 454 kg. The toll free number of the NRC is (800) 424-8802; In the Washington D.C. metropolitan area (202) 426-2675. The rule for determining when notification is required is stated in 40 CFR 302.4 (section IV. D.3.b).

1,3-Dichloropropane was detected at levels of 18, 0.038, 0.008 and 0.012 ppm in leachate from four monitoring wells located at an abandoned organic chemical manufacturing facility near Salem, OH(1).

SOURCE DOMINATED: 1,3-Dichloropropane was detected in the air near an unspecified industrial site at a concn of 2 ppb(1).

moderately toxic

There is no evidence that 1,3-dichloropropane is manufactured or used commercially in the United States(SRC), although it may be produced as a result of the photochlorination of isopropyl ether(1). 1,3-Dichloropropane may also have been a low level impurity in 1,2-dichloropropane and 1,3-dichloropropene production(2).

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 290(SRC), determined from a log Kow of 2.0(2) and a regression-derived equation(3), indicates that 1,3-dichloropropane is expected to have moderate mobility in soil(SRC). Volatilization of 1,3-dichloropropane from moist soil surfaces is expected to be an important fate process(SRC) given a Henry's Law constant of 9.76X10-4 atm-cu m/mole(4). The potential for volatilization of 1,3-dichloropropane from dry soil surfaces may exist (SRC) based upon a vapor pressure of 18.2 mm Hg(5). Using a standard dilution method and a sewage seed inoculum, 1,3-dichloropropane achieved 16% of the theoretical BOD during a 5 day incubation period(6), suggesting biodegradation may occur in soil(SRC). The hydrolysis half-life of 1,3-dichloropropane is 2.3 years at pH 7 and 25 °C(7), suggesting hydrolysis will occur slowly in moist soils(SRC).|AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 290(SRC), determined from a log Kow of 2.0(2) and a regression-derived equation(3), indicates that 1,3-dichloropropane is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(3) based upon a Henry's Law constant of 9.76X10-4 atm-cu m/mole(4). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 2 hours and 4.5 days, respectively(SRC). According to a classification scheme(5), an estimated BCF of 7(SRC) from its log Kow(2) and a regression-derived equation(6), suggests the potential for bioconcentration in aquatic organisms is low. The hydrolysis half-life of 1,3-dichloropropane is 2.3 years at pH 7 and 25 °C(7). Using a standard dilution method and a sewage seed inoculum, 1,3-dichloropropane achieved 16% of the theoretical BOD during a 5 day incubation period(8), suggesting biodegradation may occur in water(SRC).|ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), 1,3-dichloropropane, which has a vapor pressure of 18.2 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase 1,3-dichloropropane is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 21 days(SRC), calculated from its rate constant of 7.8X10-13 cu cm/molecule-sec at 25 °C(3).

The hydrolysis rate constant of 1,3-dichloropropane was measured in dilute aqueous solutions within the temperature ranges of 101 to 190 °C (neutral range) and 85 to 132 °C (basic range), and at pH values of 3 to 13. The environmental half life of 1,3-dichloropropane (at 25 °C, pH 7) is 2.2 yr.|The rate constant for the vapor-phase reaction of 1,3-dichloropropane with photochemically-produced hydroxyl radicals has been measured as 7.8X10-13 cu cm/molecule-sec at 25 °C(1). This corresponds to an atmospheric half-life of about 21 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1). The hydrolysis half life of 1,3-dichloropropane (at 25 °C, pH 7) is 2.3 years(2).

An estimated BCF of 7 was calculated for 1,3-dichloropropane(SRC), using a log Kow of 2.0(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low.

The Koc of 1,3-dichloropropane is estimated as 290(SRC), using a measured log Kow of 2.0(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that 1,3-dichloropropane is expected to have moderate mobility in soil.

The Henry's Law constant for 1,3-dichloropropane is 9.76X10-4 atm-cu m/mole(SRC)(1). This Henry's Law constant indicates that 1,3-dichloropropane is expected to volatilize from water surfaces(2). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec)(2) is estimated as 2 hours(SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec)(2) is estimated as 4.5 days(SRC). 1,3-Dichloropropane's Henry's Law constant(1) indicates that volatilization from moist soil surfaces may occur(SRC). The potential for volatilization of 1,3-dichloropropane from dry soil surfaces may exist(SRC) based upon a vapor pressure of 18.2 mm Hg(3). The volatilization half-lives of 1,3-dichloropropane in laboratory beakers stirred at 250 rpm and 25 °C from freshwater and seawater were 69 and 81 minutes, respectively(4).

GROUNDWATER: 1,3-Dichloropropane was detected in 5 of 42 wells from Canada (1992-1994) at concns of 0.15-0.76 ug/l(1).

Inhalation of vapor, ingestion, eye, and skin contact|Since this compound is apparently not produced or used in the United States, general population exposure and occupational exposure is expected to be very low or non-existent. (SRC)

1,3-Dichloropropane was identified, not quantified, in human adipose tissue(1).

INHALATION: May cause some central nervous system depression. EYES: May cause some pain and irritation. SKIN: Mild irritation. (USCG, 1999)

Call a doctor. INHALATION: Remove to fresh air. If breathing has stopped, give artificial respiration. EYES: Flush with running water for 15 minutes. SKIN: Wash thoroughly with soap and water. INGESTION: Gastric lavage or emesis and catharsis. (USCG, 1999)

Fresh air, rest.

First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

1. FLUSH contaminating fumigants from the skin and eyse with copious amounts of water or saline for at least 15 minutes. Some fumigants are corrosive to the cornea and may cause BLINDNESS. Specialized medical treatment should be obtained promptly following removal of toxicant by copious flushing with clean water. Skin contamination may cause BLISTERING and deep chemical burns. Absorption of some fumigants across the skin may be sufficient to cause systemic poisoning in the absence of fumigant inhalation. For all these reasons, decontamination of eyes and skin must must be IMMEDIATE and THROUGH. 2. REMOVE victims of fumigant inhalation to FRESH AIR immediately. Even though initial symptoms and signs are mild, keep the victim quiet, in a semi-reclining position. Minimum pohysical activity limits the likehood ofpulmonary edema. 3. If victim is not breathing, clear the airway of secretions and RESUSCITATE with positive poressure oxygen apparatus. If this is not available, use chest compression to sustain respiration. If victim is pulseless, employ cardiac resuscitation. 4. If PULMONARY EDEMA is evident, there are several measures avilable to sustain life. Medical judgement must be relied upon, however, in the management of each case. The following procedures are generally recommended: A. Put the victim in a SITTING position with a backrest. B. Use intermittent and/or continuous positive pressure OXYGEN to relieve hypoxemia. ... C. Slowly administer FUROSEMIDE, 40 mg, or SODIUM ETHACRYNATE, 50 mg, to reduce venous load by inducing diuresis. ... D. Morphine in small doses (5-10 mg), slowly, iv to allay anxiety and promote deeper respiratory excursions. E. Administer AMINOPHYLLINE (0.25-0.50 gm) slowly, iv. ... F. Digitalization may be considered, but there is a serious risk of arrhythmias in an anoxic and toxic myocardium. G. TRACHEOSTOMY may be necessary in some cases to facilitate aspiration of large amounts of pulmonary edema fluid. H. Epinephrine, atorpine, and expectorants are generally not helpful, and may complicate treatment. I. Watch for RECURRENT PULMONARY EDEMA, even up to 2 weeks after the initial episode. Limit victim's physical activity for at least 4 weeks. Severe physical weakness usually indicates persistent pulmonary injury. Serial pulmonary function testing may be useful in assessing recovery. 5. Combat SHOCK by placing victim in the Trendelenburg position and administering plasma, whole blood, and/or electrolyte and glucose solutions intravenously, with great care, to avoid pulmonary edema. Central venous pressure should be monitored continously. Vasopressor amines must be given with great caution, because of the irritability of the myocardium. 6. Control CONVULSIONS. Seizures are most likely to occur in poisonings by methyl bromide, hydrogen cyanide, acrylonitrile, phosphine, and carbon disulfide. ... /Fumigant poisoning/|7. If a FUMIGANT LIQUID OR SOLID has been INGESTED less than several hours prior to treatment, quantities remaining in the stomach must be removed as effectively as possible by gastric intubation, aspiration, and lavage, after all possible precautions have been taken to protect the respiratory tract from aspirated gasric contents. A. Put in place a cuffed ENDOTRACHEAL TUBE prior to gastric intubation. Administer OXYGEN, using a mechanical ventilator if respiration is depressed. B. Lavage the stomach with a slurry of ACTIVATED CHARCOAL in saline or water. Leave a volume of the slurry in the stomach with an appropriate dose of sorbitol as cathartic ... . C. If treatment is delayed and if the patient remains fully alert, adminsiter activated charcoal and sorbitol orally. ... Repeated administration of charcoal at half or more the initial dosage every 2-4 hours may be beneficial. D. Do not given vegetable or animal fats or oils, which enhance gastrointestinal absorption of many of the fumigant compounds. 8. Intravenous infusions of GLUCOSE are valuable in limiting the heptotoxicity of many substances. Monitor central venous presure to avoid precipitating, or aggravating, pulmonary edema by fluid overlaod. The victim should be watched closely for indications of delayed or recurrent pulmonary edema, and for bronchophenumonia. Fluid balance should be monitored, and urine sediment should be checked regularly for indications of tubular injury. Measure serum alkaline phosphatase, LDH, ALT, AST, and bilirubin to assess liver injury. 9. HEMOPERFUSION OVER ACTIVATED CHARCOAL has been used in managing a case of carbon tetrachloride poisoning with apparent success. ... 10. EXTRACORPOREAL HEMODIALYSIS may be needed to regulate extracellular fluid composition if renal failure supervenes. It is probably not very effective in removing lipophilic fumigant compounds from blood, but is, of course, effective in controlling extracellular fluid composition if renal failure occurs. /Fumigant poisoning/|Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal ... . Cover skin burns with dry sterile dressings after decontamination ... . /Dichloropropane, dichloropropene, and related compounds/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious or in severe respiratory distress. Positive pressure ventilation techniques with a bag valve mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start an IV D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Consider drug therapy for pulmonary edema ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Dichloropropane, dichloropropene, and related compounds/|Stabilization: Treatment is largely supportive. Watch for respiratory depression & arrhythmias. Obtain arterial blood gases. Administer oxygen if there is evidence of altered mental status or dyspnea. Treat hypotension with volume expansion & vasopression. Use lidocaine or beta-blockers for ventricular arrhythmias. Skin: Remove contaminated clothing. Wash affected area with soap & copious amounts or water. Eye: Irrigate the eye for 15-20 min. Obtain a consultation if symptoms persist. Oral: Most of the halogenated solvents ingested in quantities of 1-2 swallows may be partially removed by ipecac-induced emesis if admin within a few hr to a patient who has not lost the gag reflex, is not seizing, is not markedly lethargic, or is not in coma. Observe the patient in the upright position to lessen the possibility of aspiration. Activated charcoal is probably ineffective. Inhalation: Move from the contaminated area. Provide a source of oxygen & prepare for mechanical ventilation. If the patient is unconscious & the pulse is absent, initiate CPR measures. Enhancement of Elimination: Maintain good ventilation. Hemodialysis or hemoperfusion are not likely to be useful because of the high lipophilic properties of these solvents. Antidote: N-acetylcysteine may restore depleted glutathione stores, but no adequate clinical studies are available to validate this possible treatment. Supportive Care: Watch for cardiac dysrhythmias, aspiration pneumonitis, hepatotoxicity, & hypoxic encephalopathy. Monitor for arrhythmia for at least 24 hr & for hepatorenal failure for about 3 days. Obtain a chest x-ray, arterial blood gas, EKG, serum creatinine, & hepatic aminotransferase. Check electrolyte imbalance daily. Treat renal failure with dialysis & hepatic failure with fresh frozen plasma, vitamin K, a low-protein diet, neomycin, & lactulose. Watch fluid & electrolyte balance. /Halogenated hydrocarbons/

Vapors cause a slight smarting of eyes & resp system if present in high concn. The effect is temporary. ... If spilled on clothing & allowed to remain, may cause smarting & reddening of skin. ... Alters pancreatic function /as late effect/.|Symptomatology: 1A) Inhalation, high vapor concn: gasping, refusal to breathe, coughing, substernal pain, & extreme respiratory distress at vapor concn over 1500 ppm. Irritation of eyes & upper respiratory mucosa appears promptly after exposure to concentrated vapors. Lacrimation & headache are prominent. Coma may occur rapidly. B) Inhalation, low vapor concn: central nervous depression & moderate irritation of respiratory system. Headache is frequent. 2) Dermal: severe skin irritation with marked inflammatory response of epidermis & underlying tissues. 3) Oral: acute gastrointestinal distress with pulmonary congestion & edema. Central nervous depression, perhaps even in the absence of impaired oxygen uptake. 4) By any route, possible late injuries to liver, kidneys & heart. 5) After inhalation exposures, malaise, headache, chest & abdominal discomfort & irritability have been reported to persist for several weeks & perhaps for several years.

1,3-dichloropropane

The substance can be absorbed into the body by inhalation and by ingestion.

Dizziness.

Redness. Pain.

Redness. Pain.

No evidence of commercial prodn or sales of the isolated cmpd in USA in 2000.

All other basic organic chemical manufacturing|Propane, 1,3-dichloro-: ACTIVE|PART OF DICHLOROPROPENE-DICHLOROPROPANE MIXT (PROBABLE USE)|Photochlorination of isopropyl ether leads to 1,3-dichloropropane.

Purge-and-trap analysis using fused silica capillary column gas chromatography/mass spectrometry was evaluated for the analysis of priority pollutants. Using EPA volatile organic performance evaluation samples, WP006 & WP007 as unknown test materials, satisfactory precision (8.5%) & excellent accuracy (98.5% & 102% recoveries) were achieved. The capillary column was much faster than the packed column (13 min compared to 33 min) & overcame difficulties normally encountered with samples having excessive complexity, very large concn spread among components, or high concn of high-boiling components.|EAD Method 1624. Volatile Organic Compounds by Isotope Dilution GCMS. Detection limit= 10.0 ug/l.|EMSLC Method 524.2. Measurement of Purgeable Organic Compounds in Water by Capillary Column Gas Chromatography/Mass Spectrometry. Revision 4.0. Detection limit= 0.040 ug/l.|EMSLC Method 524.1. Measurement of Purgeable Organic Compounds in Water by Packed Column Gas Chromatography and Mass Spectrometry. Revision 3.0. Detection limit = 0.100 ug/l.|For more Analytic Laboratory Methods (Complete) data for 1,3-DICHLOROPROPANE (7 total), please visit the HSDB record page.