(2-METHYL-1,2,3,4-TETRAHYDRO-QUINOLIN-4-YL)-PHENYL-AMINE

Will dissolve in 200μLOrganic photocatalyst DPZ in toluene (0.28 mg, 0.0008 mmol)Take a 10mL reaction flask, Dry the toluene with an air pump and add 66 mg (0.4 mmol)2-phenylaminopropionic acid and 100mg 4Å molecular sieves, Then add 4mL purified and dried chloroform and seal the bottle mouth with a rubber stopper.And insert a balloon filled with dry air. Place the reaction flask in a 25°C incubator.The reaction was stirred for 15 hours under the irradiation of two 1W blue LED lamps.After the reaction is complete, use a rotary evaporator to distill 2/3 of the solution.Separation by column chromatography (hexane/ethyl acetate 60-30:1)That is, 39.1 mg of 2-methyl-4-N-phenyl-tetrahydroquinolin-4-amine are obtained as a colorless oily liquid.The yield was 82percent.Will dissolve in 200μLOrganic photocatalyst DPZ in toluene (0.28 mg, 0.0008 mmol)Take a 10mL reaction flask, Dry the toluene with an air pump and add 66 mg (0.4 mmol)2-phenylaminopropionic acid and 100mg 4Å molecular sieves, Then add 4mL purified and dried chloroform and seal the bottle mouth with a rubber stopper.And insert a balloon filled with dry air. Place the reaction flask in a 25°C incubator.The reaction was stirred for 15 hours under the irradiation of two 1W blue LED lamps.After the reaction is complete, use a rotary evaporator to distill 2/3 of the solution.Separation by column chromatography (hexane/ethyl acetate 60-30:1)That is, 39.1 mg of 2-methyl-4-N-phenyl-tetrahydroquinolin-4-amine are obtained as a colorless oily liquid.The yield was 82percent.

Molecular Weight:238.33
XLogP3:4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:238.146998583
Monoisotopic Mass:238.146998583
Topological Polar Surface Area:24.1
Heavy Atom Count:18
Complexity:260
Undefined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes