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Home > Encyclopedia > Polymyxin B, N-sulfomethyl deriv., sodium salt

Polymyxin B, N-sulfomethyl deriv., sodium salt

pharmaceutical raw materials
Polymyxin B, N-sulfomethyl deriv., sodium salt structure

Polymyxin B, N-sulfomethyl deriv., sodium salt 

structure
  • CAS No:

    1407-09-6

  • Chemical Name:

    Polymyxin B, N-sulfomethyl deriv., sodium salt

  • Synonyms:

    Polymyxin B,N-sulfomethyl deriv.,sodium salt;Thiosporin;Polymyxin B methanesulfonate;Polymyxin B-methanesulfonic acid;8060-25-1;11006-58-9

  • Categories:

    Active Pharmaceutical Ingredients  >  Antibiotics

Polymyxin B, N-sulfomethyl deriv., sodium salt Basic Attributes

215-802-8

Polymyxin B, N-sulfomethyl deriv., sodium salt Use and Manufacturing

Methods of Manufacturing

It is obtained by fermentation of Bacillus polymyxa var. colistinus. (1) Process of Japan's Asahi Kasei Co., Ltd. The myxobacteria culture solution is dried and made into sulfate. (2) Process of Meiji Pharmaceutical Co., Ltd., Japan. The pH of the fermentation broth is adjusted, the solid is removed by filtration, the colistin in the liquid is adsorbed by ion exchange resin, the hydrochloride is made after elution, and then concentrated and dried.

Uses

The antibacterial spectrum and antibacterial mechanism of this product are the same as polymyxin E, but stronger than the latter. Mainly used for sepsis, acute enteritis, urinary tract infections, dysentery, pertussis, respiratory system infections, biliary tract infections, mixed infections of Pseudomonas aeruginosa, and ENT infections.

Drug Function and Efficacy

Not described in detail

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Registered Holders

  • Jiangsu Lianhuan Pharmaceutical Co., Ltd.

    China China
    Active

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