 Home > Encyclopedia > Propanidid

Propanidid

Propanidid structure

CAS No:
1421-14-3
Formula:
C18H27NO5
Chemical Name:
Propanidid
Synonyms:
Benzeneacetic acid,4-[2-(diethylamino)-2-oxoethoxy]-3-methoxy-,propyl ester;Acetic acid,[4-[(diethylcarbamoyl)methoxy]-3-methoxyphenyl]-,propyl ester;FBA 1420;[4-[(Diethylcarbamoyl)methoxy]-3-methoxyphenyl]acetic acid propyl ester;Epontol;Propanidid;Propanidide;Propyl 4-(N,N-diethylcarbamidomethoxy)-3-methoxy-phenylacetate;Propyl [4-[(diethylcarbamoyl)methoxy]-3-methoxyphenyl]acetate;BAY 1420;Sombrevin;Propantan;Fabantol;Fabontal;13245RP;2180TH;TH 2180;WH 5668
Categories:
Active Pharmaceutical Ingredients > Anesthetic Agents

Description

Propanidid is a member of methoxybenzenes.|An intravenous anesthetic that has been used for rapid induction of anesthesia and for maintenance of anesthesia of short duration. (From Martindale, The Extra Pharmacopoeia, 30th ed, p918)

Propanidid Basic Attributes

Molecular Weight：

337.41068

Exact Mass：

337.41

EC Number：

215-822-7

UNII：

AO82L471NS

DSSTox ID：

DTXSID7048825

ATC Code：

N - Nervous system

HScode：

2924299090

Characteristics

PSA：

65.07000

XLogP3：

2.43810

Density：

1.087g/cm3

Melting Point：

<25 °C

Boiling Point：

211 °C

Flash Point：

231.8ºC

Refractive Index：

1.503

Vapor Pressure：

1.24E-08mmHg at 25°C

Drug Information

MeSH：

Ultrashort-acting anesthetics that are used for induction. Loss of consciousness is rapid and induction is pleasant, but there is no muscle relaxation and reflexes frequently are not reduced adequately. Repeated administration results in accumulation and prolongs the recovery time. Since these agents have little if any analgesic activity, they are seldom used alone except in brief minor procedures. (From AMA Drug Evaluations Annual, 1994, p174) (See all compounds classified as Anesthetics, Intravenous.)

MeSH Entry Terms：

Epontol

Computed Properties

Molecular Weight:337.4
XLogP3:2.8
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:11
Exact Mass:337.18892296
Monoisotopic Mass:337.18892296
Topological Polar Surface Area:65.1
Heavy Atom Count:24
Complexity:384
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes