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Ginsenoside Rd

pharmaceutical raw materials
Ginsenoside Rd structure

Ginsenoside Rd 

structure
  • CAS No:

    52705-93-8

  • Formula:

    C48H82O18

  • Chemical Name:

    Ginsenoside Rd

  • Synonyms:

    β-D-Glucopyranoside,(3β,12β)-20-(β-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-;Dammarane,β-D-glucopyranoside deriv.;(3β,12β)-20-(β-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside;Ginsenoside Rd;Gypenoside VIII;3-O-β-D-Glucopyranosyl-(1→2)-β-D-glucopyranosyl-20-O-β-D-glucopyranosyldammar-24-ene-3β,12β,20S-triol;Chikusetsusaponin FK7;Ginsenoside Rd1;52286-60-9;87700-08-1;212055-73-7

  • Categories:

    Cosmetic Ingredient  >  Antioxidant Ingredient

Description

Ginsenoside Rd inhibits TNFα-induced NF-κB transcriptional activity with an IC50 of 12.05±0.82 μM in HepG2 cells. Ginsenoside Rd inhibits expression of COX-2 and iNOS mRNA. Ginsenoside Rd also inhibits Ca2+ influx. Ginsenoside Rd inhibits CYP2D6, CYP1A2, CYP3A4, and CYP2C9, with IC50s of 58.0±4.5 μM, 78.4±5.3 μM, 81.7±2.6 μM, and 85.1±9.1 μM, respectively.

Ginsenoside Rd Basic Attributes

963.15

947.15

258-118-5

29389090

Characteristics

298.14000

-0.02680

1.4±0.1 g/cm3

204-206 °C

1020.4°C at 760 mmHg

568.0±34.3 °C

1.611

2-8°C

Safety Information

NONH for all modes of transport

3

22

2-45

Xn

H302

Ginsenoside Rd Use and Manufacturing

Ginsenoside Rd is a protopanaxadiol type saponin, which has various effects in vitro and in vivo, including cardiovascular and neuroprotection, anti-inflammatory and so on.

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