Ginsenoside Rc
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Ginsenoside Rc
structure -
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CAS No:
11021-14-0
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Formula:
C53H90O22
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Chemical Name:
Ginsenoside Rc
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Synonyms:
β-D-Glucopyranoside,(3β,12β)-20-[(6-O-α-L-arabinofuranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-;Dammarane,β-D-glucopyranoside deriv.;(3β,12β)-20-[(6-O-α-L-Arabinofuranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside;Ginsenoside Rc;Panaxoside Rc;NSC 310104;52286-73-4;52590-96-2;75047-29-9;212055-72-6
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CAS No:
Description
Ginsenoside Rc, one of major Ginsenosides from Panax ginseng, enhances GABA receptorA (GABAA)-mediated ion channel currents (IGABA). Ginsenoside Rc inhibits the expression of TNF-α and IL-1β.
Solid
2-[[2-[[17-[2-[[6-[[3,4-dihydroxy-5-(hydroxymethyl)-2-oxolanyl]oxymethyl]-3,4,5-trihydroxy-2-oxanyl]oxy]-6-methylhept-5-en-2-yl]-12-hydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)-3-oxanyl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol is a steroid saponin.
Characteristics
357
-1.56350
Solid
1.4±0.1 g/cm3
193-196 °C
1128.3°C at 760 mmHg
636.2±34.3 °C
1.622
2-8°C
0mmHg at 25°C
Safety Information
NONH for all modes of transport
3
20/21/22
26-36
LY9536300
Xn
P280
H302-H312-H332
|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P312, P322, P330, P363, and P501|Aggregated GHS information provided by 43 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Ginsenoside Rc Use and Manufacturing
Ginsenoside Rc belongs to steroids and triterpenoid saponins. It is unique in ginseng plants and has the characteristics of inhibiting or preventing tumor growth.
Computed Properties
Molecular Weight:1079.3
XLogP3:0.9
Hydrogen Bond Donor Count:14
Hydrogen Bond Acceptor Count:22
Rotatable Bond Count:16
Exact Mass:1078.59237449
Monoisotopic Mass:1078.59237449
Topological Polar Surface Area:357
Heavy Atom Count:75
Complexity:1950
Undefined Atom Stereocenter Count:29
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Drug Function and Efficacy
The main pharmacodynamic tests have confirmed that oral administration of ginsenoside Rg3 has an inhibitory effect on a variety of animal transplanted solid tumors. Combined with chemotherapy, it has an enhanced therapeutic effect on H22 ascites liver cancer in mice, and can regulate immune function, prevent leukopenia, hair loss, etc. The drug can also inhibit the proliferation and growth of tumor vascular endothelial cells and the formation of new blood vessels.
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RC 161
103237-51-0
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53963-43-2
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Ginsenoside Re Formula
52286-59-6
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Ginsenoside Rb1 Formula
41753-43-9
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Ginsenoside Rb2 Formula
11021-13-9
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Ginsenoside Rh4 Structure
174721-08-5
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Ginsenoside Rf Structure
52286-58-5
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What is Ginsenoside K
39262-14-1
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What is Ginsenoside Rh2
78214-33-2