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Ginsenoside Rc

Ginsenoside Rc structure

CAS No:
11021-14-0
Formula:
C53H90O22
Chemical Name:
Ginsenoside Rc
Synonyms:
β-D-Glucopyranoside,(3β,12β)-20-[(6-O-α-L-arabinofuranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-;Dammarane,β-D-glucopyranoside deriv.;(3β,12β)-20-[(6-O-α-L-Arabinofuranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside;Ginsenoside Rc;Panaxoside Rc;NSC 310104;52286-73-4;52590-96-2;75047-29-9;212055-72-6
Categories:
Biochemical Engineering > Plant Extracts

Description

Ginsenoside Rc, one of major Ginsenosides from Panax ginseng, enhances GABA receptorA (GABAA)-mediated ion channel currents (IGABA). Ginsenoside Rc inhibits the expression of TNF-α and IL-1β.

Solid

2-[[2-[[17-[2-[[6-[[3,4-dihydroxy-5-(hydroxymethyl)-2-oxolanyl]oxymethyl]-3,4,5-trihydroxy-2-oxanyl]oxy]-6-methylhept-5-en-2-yl]-12-hydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)-3-oxanyl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol is a steroid saponin.

Ginsenoside Rc Basic Attributes

Molecular Weight：

1079.27

Exact Mass：

1079.27

EC Number：

234-253-5

NSC Number：

310104

Characteristics

PSA：

357

XLogP3：

-1.56350

Appearance：

Solid

Density：

1.4±0.1 g/cm3

Melting Point：

193-196 °C

Boiling Point：

1128.3°C at 760 mmHg

Flash Point：

636.2±34.3 °C

Refractive Index：

1.622

Storage Conditions：

2-8°C

Vapor Pressure：

0mmHg at 25°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

20/21/22

safety instructions：

26-36

RTECS Number：

LY9536300

Marks：

Precautionary statement(s)：

P280

Hazard Statements：

H302-H312-H332

GHS Classification：

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P312, P322, P330, P363, and P501|Aggregated GHS information provided by 43 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Ginsenoside Rc Use and Manufacturing

Ginsenoside Rc belongs to steroids and triterpenoid saponins. It is unique in ginseng plants and has the characteristics of inhibiting or preventing tumor growth.

Computed Properties

Molecular Weight:1079.3
XLogP3:0.9
Hydrogen Bond Donor Count:14
Hydrogen Bond Acceptor Count:22
Rotatable Bond Count:16
Exact Mass:1078.59237449
Monoisotopic Mass:1078.59237449
Topological Polar Surface Area:357
Heavy Atom Count:75
Complexity:1950
Undefined Atom Stereocenter Count:29
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

The main pharmacodynamic tests have confirmed that oral administration of ginsenoside Rg3 has an inhibitory effect on a variety of animal transplanted solid tumors. Combined with chemotherapy, it has an enhanced therapeutic effect on H22 ascites liver cancer in mice, and can regulate immune function, prevent leukopenia, hair loss, etc. The drug can also inhibit the proliferation and growth of tumor vascular endothelial cells and the formation of new blood vessels.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Shenyi Capsule
Ingredients	Ginsenoside R, (, insenosideR,).
Indication	Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Specifications	Each capsule contains ginsenoside Rg310mg
Manufacturer	Jilin Yatai Pharmaceutical Co., Ltd.

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Learn More Other Chemicals

Ginsenoside Rf

52286-58-5
Ginsenoside Rb2

11021-13-9
Ginsenoside Rh2

78214-33-2
Ginsenoside La Formula

123617-34-5
Ginsenoside Rh4 Formula

174721-08-5
RC 161 Formula

103237-51-0
Ginsenoside Re Structure

52286-59-6
Ginsenoside Rb1 Structure

41753-43-9
What is Ginsenoside F1

53963-43-2
What is Ginsenoside K

39262-14-1

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Guide of Ginsenoside Rc

Description
Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Computed Properties
Drug Function and Efficacy
Related Drugs
Recommended Suppliers
Learn More Other Chemicals

Ginsenoside Rc

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