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Flibanserin

Flibanserin structure

CAS No:
167933-07-5
Formula:
C20H21F3N4O
Chemical Name:
Flibanserin
Synonyms:
2H-Benzimidazol-2-one,1,3-dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-;1,3-Dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-2H-benzimidazol-2-one;BIMT 17;Flibanserin;BIMT 17BS;Addyi;1-(2-[4-[3-(Trifluoromethyl)phenyl]piperazin-1-yl]ethyl)-1,3-dihydro-2H-benzimidazol-2-one
Categories:
Active Pharmaceutical Ingredients > Hormones and the Endocrine System

Description

Flibanserin is a novel multifunctional serotonin agonist and antagonist (MSAA) that improves sexual functioning in premenopausal women who suffer from reduced sexual interest and desire.IC50 value:Target: serotoninin vivo: The multifunctional serotonergic agent Flibanserin is both a serotonin 1A agonist and a serotonin 2A antagonist. Flibanserin theoretically improves sexual functioning by enhancing downstream release of dopamine and norepinephrine while reducing serotonin release in the

Flibanserin Basic Attributes

Molecular Weight：

390.4

Exact Mass：

390.40

EC Number：

1806241-263-5

Characteristics

PSA：

38.8

XLogP3：

3.3

Appearance：

white to beige

Density：

1.292 g/cm3

Refractive Index：

1.566

Water Solubility：

DMSO: soluble10mg/mL, clear

Storage Conditions：

2-8°C

Vapor Pressure：

3.13X10-10 mm Hg at 25 deg C (est)

Safety Information

Transport codes：

UN 2811 6.1 / PGIII

hazard class code：

25-36/37/38

safety instructions：

26-45

Marks：

Stability/Shelf Life：

Stable under recommended storage conditions.

Precautionary statement(s)：

P261-P301 + P310-P305 + P351 + P338

Hazard Statements：

H301-H315-H319-H335

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