Sodium dihydrogen phosphate dihydrate
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Sodium dihydrogen phosphate dihydrate
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CAS No:
13472-35-0
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Formula:
H3O4P.2H2O.Na
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Chemical Name:
Sodium dihydrogen phosphate dihydrate
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Synonyms:
Phosphoric acid,sodium salt,hydrate (1:1:2);Phosphoric acid,monosodium salt,dihydrate;Sodium dihydrogen phosphate dihydrate;Monosodium phosphate dihydrate;Sodium phosphate (NaH2PO4) dihydrate;Monosodium dihydrogen phosphate dihydrate;53807-02-6
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CAS No:
Description
White crystalline solid. The USP 32 states that monobasic sodium phosphate contains one or two molecules of water of hydration or is anhydrous. The hydrated forms of monobasic sodium phosphate occur as odorless, colorless or white, slightly deliquescent crystals. The anhydrous form occurs as a white crystalline powder or granules. Sodium Dihydrogen Phosphate occurs as two forms: the crystal form (dihydrate) called Sodium Dihydrogen Phosphate (crystal) and anhydrous form called Sodium Dih.
Characteristics
82.6
-0.61900
White Solid
1,915 g/cm 3
60 °C
158ºC at 760 mmHg
1.4629
H2O: soluble
Store at +5°C to +30°C.
LD50 orally in Rabbit: 8290 mg/kg LD50 dermal Rabbit > 7940 mg/kg
Safety Information
NONH for all modes of transport
1
36-36/37/38
39-26-24/25-36
WA1900500
Xi
Aqueous solutions are stable and may be sterilized by autoclaving.
Monobasic sodium phosphate should be stored in an airtight
container in a cool, dry place.
Stable.
Sodium dihydrogen phosphate dihydrate Use and Manufacturing
Use the neutralization method. It is obtained by neutralizing phosphoric acid with soda ash or sodium hydroxide: adding sodium hydroxide or soda ash to concentrated phosphoric acid to control the pH to 4.4-4.6. The neutralized solution is filtered, concentrated, and then cooled to crystallize below 41°C. Centrifuged and dried products
Monobasic sodium phosphate is used in a wide variety of
pharmaceutical formulations as a buffering agent and as a
sequestering agent. Therapeutically, monobasic sodium phosphate
is used as a mild saline laxative and in the treatment of hypophosphatemia.
Monobasic sodium phosphate is also used in food products, for
example, in baking powders, and as a dry acidulant and
sequestrant.
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Sodium dihydrogen phosphate dihydrate
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