3-Chlorophenol Safety Data Sheets

Acute toxicity - Category 4, Oral

Acute toxicity - Category 4, Dermal

Acute toxicity - Category 4, Inhalation

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2

If inhaled

Following skin contact

Following eye contact

Following ingestion

SYMPTOMS: Symptoms of exposure to this compound include irritation, burns and corrosion of the eyes, skin, mucous membranes and upper respiratory tract. It may also cause restlessness, increase in rate of respiration, motor weakness, tremors, clonic convulsions, dyspnea, coma and death. ACUTE/CHRONIC HAZARDS: This compound is toxic by inhalation, ingestion and skin absorption. When heated to decomposition it emits toxic fumes of carbon monoxide, carbon dioxide and hydrogen chloride gas. This compound may be corrosive. (NTP, 1992)

This chemical is probably combustible. (NTP, 1992)

Use water spray, foam, powder, carbon dioxide.

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.

Phenolic cmpd in wastewater are oxidized with hydrogen peroxide catalyzed by iron(3+)-iron(2+). When the wt ratio of phenol:hydrogen peroxide is 1:3 and iron 5-100 ppm, more than 95% of the phenols are removed in 30 min from a 500 ppm phenol soln at pH 5-6 and 25-50 deg C. Phenolic cmpd

NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Separated from strong oxidants and food and feedstuffs. Well closed.Store in tightly closed containers in a cool, well ventilated area. Metal containers involving the transfer of this chemical should be grounded and bonded. Where possible, automatically pump liquid from drums or other storage containers to precess containers. Drums must be equipped with self-closing valves, pressure vacuum bungs, and flame arresters. Use only non-sparking tools and equipment, especially when opening and closing containers of this chemical. Sources of ignition such as smoking and open flames, are prohibited where this chemical is used, handled, or stored in a manner that could create a potential fire or explosion hazard. Monochlorophenols

Occupational Exposure limit values

Biological limit values

Eye/face protection

Skin protection

Respiratory protection

Thermal hazards

Decomposes on heating. This produces toxic and corrosive fumes of hydrogen chloride (see ICSC 0163) and chlorine (see ICSC 0126). Reacts with oxidants.

Discolors on exposure to air.

M-CHLOROPHENOL is incompatible with acid chlorides, acid anhydrides and oxidizing agents (NTP, 1992).

no data available

no data available

When heated to decomposition it emits toxic fumes of /hydrogen chloride/.

Acute toxicity

• Oral: LD50 Rat oral 0.56 mL/kg
• Inhalation: no data available
• Dermal: no data available

Skin corrosion/irritation

Serious eye damage/irritation

Respiratory or skin sensitization

Germ cell mutagenicity

Carcinogenicity

Reproductive toxicity

STOT-single exposure

STOT-repeated exposure

Aspiration hazard

• Toxicity to fish: LC50; Species: Oncorhynchus mykiss (Rainbow trout); Conditions: freshwater, renewal,14.5-15.5 deg C, pH 8.0, dissolved oxygen 9.5-10.4 mg/L; Concentration: 10,000 ug/L for 48 hr /formulated product
• Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna (Water flea, age <72 hr) Conditions: freshwater, static, 20 deg C, pH 7.8-8.2, hardness 200 mg/L CaCO3, dissolved oxygen > or = 2.27 mg/L; Concentration: 15780 ug/L for 24 hr (95% confidence interval: 13800-17750 ug/L); Effect: intoxication, immobilization />95% purity
• Toxicity to algae: EC50; Species: Pseudokirchneriella subcapitata (Green algae, exponential growth phase, 50000 cells/mL); Conditions: freshwater, static, 21 deg C; Concentration: 29000 ug/L for 96 hr; Effect: growth, general /formulated product
• Toxicity to microorganisms: no data available

AEROBIC: Biological degradation of chlorophenols in activated sludge ... 3-chlorophenol was found at a level of 100 mg/L, and was completetly degraded in three days with 100% ring degradation.

Carp exposed to 40 ug/L of 3-chlorophenol for a period of 6 weeks had BCF values in the range of 5.1-10 and carp exposed to 4 ug/L of 3-chlorophenol for a period of 6 weeks had BCF values in the range of 7.0-16(1). A BCF value of 20.0 (logBCF = 1.30) for 3-chlorophenol was reported(2). According to a classification scheme(3), these BCF values suggest that the potential for bioconcentration in aquatic organisms is low(SRC).

The Koc of 3-chlorophenol in soil was reported as 350(1). According to a classification scheme(2), this Koc value suggests that 3-chlorophenol is expected to have moderate mobility in soil(SRC). The pKa of 3-chlorophenol is 9.12(3), indicating that this compound will partially exist in the anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(4). Chlorophenols can be irreversibly immobilized by covalent bonding to soil organic matter (SOM). Irreversible binding increased with the addition of hydrogen peroxide and under anoxic conditions(5).

no data available

Product

Contaminated packaging

no data available

no data available

Information on revision

Abbreviations and acronyms

• CAS: Chemical Abstracts Service
• ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
• RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
• IMDG: International Maritime Dangerous Goods
• IATA: International Air Transportation Association
• TWA: Time Weighted Average
• STEL: Short term exposure limit
• LC50: Lethal Concentration 50%
• LD50: Lethal Dose 50%
• EC50: Effective Concentration 50%

References

• IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
• HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
• IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
• eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
• CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
• ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
• ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
• Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
• ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Other Information

Insufficient data are available on the effect of this substance on human health, therefore utmost care must be taken.See ICSCs 0849 and 0850.