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Analytical Chemistry

Standard

(±)-Desethylchloroquine

(1476-52-4)
The major product of the stereoselective human metabolism of Chloroquine, used for the therapy and prevention of malaria

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4-Nitro-2-phenoxyaniline

(5422-92-4)
4-Nitro-2-phenoxyaniline has been shown to have good AT1 Angiotension Receptor Antagonist activity when combined with Schiff bases.

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3-Desacetyl CefotaxiMe Lactone

(66340-33-8)
3-Desacetyl Cefotaxime Lactone is an impurity of Cefotaxime sodium (C242950). 3-Desacetyl Cefotaxime Lactone is also a degradation product for other cephalosporin antibiotics such as: Ceftriaxone (C245000), Cefodizime and Ceftiofur(C244700).

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1-Methyl-2-(Methylthio)iMidazole

(14486-52-3)
1-Methyl-2-(methylthio)imidazole is an impurity of Methimazole (M260300), a thiourea antithyroid agent that prevents iodine organification, thus inhibiting the synthesis of thyroxine.

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Ticabesone Propionate

(73205-13-7)
Ticabesone Propionate is an impurity of Fluticasone, an antiallergic, anti-asthmatic and anti-inflammatory agent.

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In the analysis work, it is often necessary to use a compound of good quality and accurate content, which is used as a comparison for detection control, or used to calibrate the instrument. This compound is called a standard. Or standard. The standard product refers to the standard substance used to determine the potency of biological products. The production department must provide the standard product expressed in units (μ) of its potency when it is approved as a quality standard for biological products. According to the application, the standard products for inspection can be divided into biological standard products for biological verification of biological products, endocrine drugs, antibiotics and so on.

Frequently Asked Questions

What are Standard Chemicals?

Standard chemicals refer to high-purity reference substances used in analytical laboratories for calibration, validation, and quality control purposes. These include certified reference materials (CRMs), analytical standards, and reagent-grade compounds that meet internationally recognized specifications such as those from USP, EP, or ISO. They ensure accuracy and reproducibility in testing across pharmaceutical, environmental, and food safety applications.

How are Standard chemicals used in laboratory analysis?

Standard chemicals are essential in laboratory analysis for tasks such as instrument calibration, method validation, quantification of unknown samples, and ensuring regulatory compliance. For example, in HPLC or GC testing, a known concentration of a chemical standard is used to create a calibration curve, which allows accurate measurement of analytes in real-world samples. Their consistent purity and traceability make them indispensable in achieving reliable test results.

Are Standard chemicals the same as reagents?

No, standard chemicals and general reagents serve different purposes. Reagents are used to cause chemical reactions during synthesis or testing but may not have precisely defined purity. In contrast, standard chemicals are highly characterized substances with exact concentrations or purities, primarily used for measurement accuracy and quality assurance. While all standards can function as reagents, not all reagents qualify as standards due to variability in composition and lack of certification.

Where can I buy certified Standard chemicals for lab use?

Certified standard chemicals can be purchased from reputable suppliers that specialize in analytical reference materials, such as Sigma-Aldrich, Merck, AccuStandard, or LGC Standards. Ensure the supplier provides full documentation—including Certificates of Analysis (CoA), traceability statements, and proper storage guidelines—and complies with ISO 17034 or similar accreditation standards. Buying from authorized distributors also minimizes the risk of counterfeit or degraded products.

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