The European Union evaluates the safety and efficacy of a 6-phytase as a feed additive for all pigs and all poultry

At the request of the European Commission, the EU Animal Feed Additives and Products (FEEDAP) research Group has issued a scientific opinion on the safety and efficacy of a 6-phytase as a feed additive for all pigs and all poultry, according to the EU Food Safety Authority (EFSA).

It is known that this 6-phytase is produced by Komagataella phaffii CGMCC 7.370. After evaluation, the panel concluded that the additive was safe for all pigs and all poultry under the proposed conditions of use. But no conclusions can be drawn about the efficacy of the additive in all pigs and all birds. Some of the original reports are as follows:

Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of 6-phytase (VTR-phytase) as zootechnical feed additive for all pigs and all avian species. The additive VTR-phytase consists of 6-phytase and it is available in solid and liquid forms. VTR phytase (liquid/solid) was produced by a genetically modified strain of Komagataella phaffii (CGMCC 7.370). The genetic modification of the production strain does not give rise to safety concerns. Viable cells of the production strain and its DNA were not detected in the final products. The additive does not pose any safety concern regarding the production strain. VTR phytase (liquid/solid) produced by Komagataella phaffii CGMCC 7.370 is safe for all Suidae and all avian species at the proposed conditions of use. The use of both forms of the additive under assessment in animal nutrition under the proposed conditions of use raises no safety concerns for consumers or for the environment. The liquid VTR phytase and powder VTR phytase are non-irritant to skin or eyes but should be considered skin and respiratory sensitisers. The additive has the potential to be efficacious in laying hens at 1,000 U phytase/kg complete feed. The additive has the potential to be efficacious in laying hens at 1,000 u phytase/kg complete feed conclusion can be extrapolated to other birds for egg production or breeding. The FEEDAP Panel cannot conclude on the efficacy of all pigs or growing poultry species.