EFSA Confirms Safety of Vitamin E TPGS as Food Additive New Opinion Covers Multiple Use Levels

On August 11, 2025, the European Food Safety Authority (EFSA) announced its expert panel has found no safety concerns for Vitamin E polyethylene glycol succinate (TPGS) as a food additive at proposed use levels. The Food Additives and Flavourings (FAF) panel concluded that Vitamin E TPGS can be safely used as an emulsifier in various food categories.

Scientific evaluation showed that TPGS is mostly monoesters (over 82%) and less than 20% diesters, with the ester bond proving stable under testing conditions. The additive is poorly absorbed and does not serve as a vitamin E source for healthy individuals. No genotoxicity or negative effects on reproduction and development were seen at doses up to 1000 mg/kg body weight per day, the highest tested.

Given the available data, the panel employed a margin of exposure (MOE) approach and determined the calculated values were sufficient to assure safety. The EFSA’s conclusion clears the way for Vitamin E TPGS to be used in foods at the proposed levels without safety concerns.