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Home > News > Blog > What Is L Citrulline DL Malate and Uses

What Is L Citrulline DL Malate and Uses

2021-12-03

L citrulline dl malate is a combination of the amino acid l citrulline and the mineral magnesium. It has several benefits for athletes, including improved physical performance and reduced fatigue. The combination has also been studied for its effectiveness in treating some medical conditions like:


  • High blood pressure
  • Erectile dysfunction
  • Sickle cell anemia

The supplement is marketed as a pre-workout product because it raises blood arginine levels to improve muscle pumps during physical activity. It can be taken with creatine monohydrate to boost overall strength training performance.


Higher arginine levels in the body naturally lower blood pressure and increase Nitric Oxide (NO) production. NO is a molecule that causes vasodilation, which leads to increased blood flow and better cardiovascular health. Here are some uses and importance of dl malate.

 

L citrulline dl malates Help Strength Training Performance

There are three main ways that arginine supplementation increases physical performance.

  • Having higher arginine levels results in improved push-up endurance. A recent study found that participants who consumed 6 grams of l citrulline dl malate for one week could do more push-ups before their arms gave out.
  • Arginine supplementation leads to improved cycling efficiency. Endurance athletes who took an arginine supplement increased their time to exhaustion by 24 percent when cycling at 75 percent of VO2 max (the maximum amount of Oxygen your body can use during exercise).
  • It increases muscle power output and strength gains. Supplementation with arginine and creatine monohydrate over ten weeks increased the bench press and squat performance.

An increase in arginine levels causes greater blood flow to work muscles during strength training. This results in better hydration, nutrient delivery, and blood flow, allowing the muscle to work harder for longer periods.

 

L citrulline dl malate Decrease Fatigue During Training

High-intensity exercise can cause fatigue because Lactic Acid builds up faster than it can be removed. Arginine supplementation reduces the accumulation of lactic acid during high-intensity exercise and increases performance, allowing athletes to train harder and for longer periods.

Arginine also gives muscles energy through creatine phosphate recycling, so it even helps with workouts that aren't as intense and require more endurance.

 

Dl malates Improve Physical Performance for Older Adults

Arginine supplementation helps improve strength, speed, and endurance for older adults. A study on 27 healthy men (ages 65-77) tested arginine's effects on physical performance compared to a placebo group. The arginine supplementation improved bench press work capacity, hand-grip strength, and stair-climbing power.

 

Dl malates Are Important in Sickle Cell Anemia Treatment

High doses of arginine through a nasogastric tube have been used to treat patients suffering from sickle cell anemia. Arginine binds with polysorbate 80 to form liposomes, which fights the painful effects of sickle cell disease and increases hemoglobin levels. Arginine also increases nitric oxide (NO) production, which relaxes blood vessels.

Nitric oxide is produced naturally in the body, but increased nitric oxide levels can be achieved through dl malate supplementation. This increases blood flow and relaxes smooth muscle tissue to prevent vasoconstriction in the erectile chambers of the penis.

 

Dl malates' Erectile Dysfunction Benefit

Dl malate increases nitric oxide levels. Nitric oxide helps blood vessels relax to allow increased blood flow. It also boosts the production of the neurotransmitters dopamine and serotonin, which helps with mood and libido problems. Nitric oxide can increase testosterone levels by increasing luteinizing hormone (LH) production and improving the testicular blood supply.

 

Dl malates Benefits for Pre-Eclampsia

Pre-eclampsia is a condition that affects pregnant women and causes high blood pressure, fluid retention, and protein in the urine. Dl malate helps with pre-eclampsia symptoms by increasing blood flow and relaxing smooth muscle tissue, like those found in the uterus.

 

Dl malates Improve Athletic Performance

Dl malate supplementation can improve athletic performance as well as exercise recovery time. The supplements increase arginine levels, which boost nitric oxide production in the body. Nitric oxide increases blood flow and oxygen to muscles during exercise. This leads to better endurance and faster recovery time.

 

Dl malates Lower Blood Pressure

Dl malate supplementation is able to lower blood pressure by relaxing smooth muscle tissue in the body. This helps decrease contractions in blood vessels, which increases blood flow and lowers blood pressure.

 

Dl malates Improve Immune System Function

Dl malate has been shown to increase white blood cell concentrations for improved immune system function. It also increases glutathione levels, an antioxidant that keeps the immune system healthy and functions as an anti-inflammatory.

Some possible negative effects of the supplementation include:

  • Nausea
  • Vomiting
  • Diarrhea.

Arginine is also associated with increased insulin levels and blood sugar since it helps transport glucose into cells. This can be beneficial if you have low blood sugar, but those with diabetes should consult a health care provider before taking arginine. Arginine can also cause low blood pressure and increased heart rate.


In some cases, arginine supplementation has been linked to chest pain and rapid heartbeat. The supplementation may also deplete the body's stores of vitamin B12. So individuals with vitamin B12 deficiency cannot take arginine supplements. Side effects are usually associated with higher doses of the supplement.

Disclaimer: ECHEMI reserves the right of final explanation and revision for all the information.

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