How far is it to become the next 'sodium hyaluronate' PQQ?
Recently, pyrroloquinoline quinone disodium salt (PQQ) was approved as a new food raw material.Because of its good effects on brain health, cardiovascular health, metabolic function health and other aspects, PQQ has been placed as the next "sodium hyaluronate" in the industry.
PQQ was accepted as a new food ingredient on 8 March 2021 and was publicly solicited for comment on 17 August of the same year.It was recently approved by the National Health Commission as a new food ingredient.It has taken less than a year, and the pace of approvals is picking up in the approval department, as can be seen.
The speed is reminiscent of sodium hyaluronate's path to fame.
According to the official website of the National Health Commission, sodium hyaluronate was declared a new food ingredient in June 2020 and was publicly solicited for comment on September 3, 2020.It was officially announced as a new food ingredient on 7 January 2021.The product was released in March 2021.To date, more than 300 foods containing sodium hyaluronate have been published online.It took just over a year from the announcement to the product explosion.
So can PQQ recreate the glory of sodium hyaluronate?
The main component of pyrroloquinone sodium salts is pyrroloquinone, also known as PQQ, a novel prosthetic group with physiological functions similar to vitamins and widely found in prokaryotes, plants, and mammals.Examples are fermented soybeans or natto, green peppers, kiwi, parsley, tea, papaya, spinach, celery, breast milk, etc.
PQQ is one of a number of enzymes responsible for the transfer of electrons, protons and chemical groups in enzymatic reactions.It can also stimulate the growth of microorganisms, germination of plant pollen, and promote plant growth.
There are two main aspects to the biological function of PQQ.First, it can support the growth and development of mitochondria and stimulate rapid growth of human cells.Second, it has good antioxidant activity, which can help remove free radicals and reduce cell damage.These two functions make it powerful in brain health, cardiovascular health, metabolic health and other aspects.Because PQQ cannot be synthesized by the body itself, it can be supplemented with dietary supplements, usually in powder form and prepared by microbial fermentation.
Common PQQ supplement products on the market today are primarily targeted at brain health, sleep aid, energy supplement, oral beauty, pregnancy aid and other aspects, and are often used in combination with MNM, coenzyme Q10, ginkgo biloba extract, PS and other ingredients.
Despite the same pace of approval, PQQ is still far from being available to consumers compared to sodium hyaluronate.
Due to the limitations of the production technology, the raw material price of PQQ is veryexpensive in the early stage and it is limited to scientific research.After years of development, Shandong Zhucheng Haotian Pharmaceutical Co Ltd and other enterprises have achieved popular consumption through cooperation with universities and research institutes.Currently, domestic concerns about PQQ are mainly in the production of raw materials, mainly for export, according to the online public figures.At the same time, there are few studies on its efficacy, which requires companies to conduct more in-depth and comprehensive research and development, and to do a good job of scientific endorsement.
In addition, when PQQ is approved as a new food ingredient, the scope of use is only for beverages, and the production process approved by the regulations is a synthetic method.Contrast hyaluronic acid sodium as a new food raw material, are added in the ordinary food use, use range from health food also extended to milk and dairy products, beverages, chocolate and chocolate products, including the generation of cocoa butter and chocolate products) and candy, frozen drinks, PQQ efficacy research, using range and production technology research is still a long way to go.
In terms of market applications, prior to its approval for general food use, sodium hyaluronate has been used in cosmetics, medical beauty products, and bone health products in China.
Sodium hyaluronate was first used as a viscoelastic preservative in eye surgery and has since been gradually applied in other fields.Known to the public as a cosmetic injection and moisturizer in cosmetics, it plays an important role in human skin as a natural moisturizing factor.Before its approval as a general food, its efficacy in skin care was widely recognized by consumers.However, the application of PQQ in the domestic market is currently often left blank and mainly focused on the international market.
PQQ can be used as an ingredient in foods such as energy drinks, sports drinks, electrolyte drinks and bottled water in the United States, and as a dietary supplement or natural health food in the European Union and Canada.
The lack of application in the domestic market has left consumers with little knowledge of its efficacy.However, if a business wants to get consumers to quickly accept and understand its health benefits when it launches a product, it needs to spend time, effort and cost to cultivate consumers and build basic consumer perception.This is a long process and an important prerequisite for PQQ to enter the market.In terms of product innovation, the rapid introduction of innovative products for sodium hyaluronate has played an integral role in driving its popularity.
The low number of applications of PQQ in the domestic market is also a testament to the fact that the number of enterprises working on PQQ will be smaller than sodium hydronate.Lacking research and development, its innovative products will be slow to reach the market.
Therefore, if we want to rely on innovative products such as sodium hyaluronate to drive the explosion of PQQ, more enterprises need to get involved to create more products with core competitiveness and promote the prosperity of PQQ in the domestic market.
Indeed, as a novel raw material, PQQ has been recognized for its positive effects on nutrition and health.Due to its powerful functionality, high safety and good stability, it has broad prospects for development in the functional food sector.
In recent years, as cognition has deepened, PQQ has achieved the most comprehensive efficacy certification and is widely used as a dietary supplement or food in the United States, Europe and other countries and regions.Among them, our PQQ products has been the first to receive regulatory approval in the United States.Currently, HAOTIAN has the top market share in the most important consumer market for PQQ in North America and is one of the most important suppliers of PQQ raw materials in the world.
With the deep awerness of domestic consumers, we believe that PQQ as a new food ingredient will create a new world in the domestic market.
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2026-07-20
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Functional Ingredients Industry Overview
Collection of Markets for Functional Ingredients in Food & Nutrition and Cosmetics.Published in: Mar. 2026
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