Indication: 1. This product can be used as a drug of choice for the following diseases: (1) Rickettsial diseases, including epidemic typhus, endemic typhus, Rocky Mountain fever, scrub typhus and Q fever; (2) Mycoplasma infections; (3) Chlamydia infections, including psittacosis, venereal diseases, lymphoedema, nonspecific urethritis, salpingitis, cervicitis and trachoma; (4) Relapsing fever; (5) Brucellosis; (6) Cholera; (7) Tularemia; (8) Plague; (9) Chancroid. It should be used in combination with aminoglycosides to treat brucellosis and plague. 2. Due to the serious drug resistance of common pathogens to this product, it can only be used as a drug of choice when the pathogens are sensitive to this product.

Indication: 1. This product can be used as a drug of choice for the following diseases: (1) Rickettsial diseases, including epidemic typhus, endemic typhus, Rocky Mountain fever, scrub typhus and Q fever; (2) Mycoplasma infections; (3) Chlamydia infections, including psittacosis, venereal diseases, lymphoedema, nonspecific urethritis, salpingitis, cervicitis and trachoma; (4) Relapsing fever; (5) Brucellosis; (6) Cholera; (7) Tularemia; (8) Plague; (9) Chancroid. It should be used in combination with aminoglycosides to treat brucellosis and plague. 2. Due to the serious drug resistance of common pathogens to this product, it can only be used as a drug of choice when the pathogens are sensitive to this product.

Indication: 1. Doxycycline is used for infections caused by the following bacteria: Rickettsia (Lasanky spotted fever, typhus fever, typhus, Q fever, Rickettsial pox, splenic fever, etc.), Mycoplasma pneumonia (pleuropneumonia-like bacteria, EatonAgent), psittacosis and ornithosis, lymphogranuloma venereum and granuloma inguinale, relapsing fever spirochetes (Borrelia burgdorferi). 2. The following Gram-positive bacteria: (1) Haemophilus ducreyi (chancroid), Pasteurella pestis and Pasteurella tularensis, rod-shaped Bartonella, Bacteroides, Vibrio comma and Vibrio embryonius, Brucella (used in combination with streptomycin). Since most of the following bacteria are resistant to tetracycline, sensitivity testing is recommended. If the bacterial sensitivity test shows a certain degree of sensitivity to the drug, doxycycline can be used for infections caused by the following Gram-negative bacteria: (2) Escherichia coli, Enterobacter aerogenes, Shigella, Mima and Hercetella, Haemophilus influenzae (respiratory tract infections), Klebsiella (respiratory and urinary tract infections). 3. Infections caused by the following Gram-positive bacteria: (1) Streptococci: 44% of Streptococcus pyogenes and 74% of Streptococcus faecalis are resistant to tetracyclines. Therefore, tetracyclines are not suitable for infections caused by streptococci unless they are highly sensitive. Penicillin is the first choice for the prevention of upper respiratory tract infections and rheumatic fever caused by type A β-hemolytic streptococci. (2) Pneumococcus, Staphylococcus aureus: respiratory tract, skin and soft tissue infections. Tetracyclines are not the first choice for staphylococcal infections. 4. When penicillin is contraindicated, doxycycline can be used as an alternative drug for infections caused by the following bacteria: (1) Neisseria gonorrhoeae and Neisseria meningitidis, Treponema pallidum and Treponema pygiene (syphilis and yaws), Listeria monocytogenes. (2) Clostridium, Bacillus anthracis, Fusobacterium fusoni, Actinomyces. 5. Doxycycline can be used as an adjunctive drug for acute intestinal amebiasis. 6. Doxycycline is still used to treat trachoma even though the infectious agent has not been eliminated as confirmed by fluorescent immunoassay.

Indication: Due to the low blood concentration of this product, its application is limited to mild and moderate infections caused by pathogens that are highly sensitive to penicillin, such as tonsillitis, scarlet fever, erysipelas, pneumonia caused by group A streptococci, furuncles, carbuncles caused by penicillin-sensitive Staphylococcus aureus, and angina. This product can also be used to treat leptospirosis, relapsing fever and early syphilis.

Indication: Due to the low blood concentration of this product, its application is limited to mild and moderate infections caused by pathogens that are highly sensitive to penicillin, such as tonsillitis, scarlet fever, erysipelas, pneumonia caused by group A streptococci, furuncles, carbuncles caused by penicillin-sensitive Staphylococcus aureus, and angina. This product can also be used to treat leptospirosis, relapsing fever and early syphilis.

Indication: Due to the low blood concentration of this product, its application is limited to mild and moderate infections caused by pathogens that are highly sensitive to penicillin, such as tonsillitis, scarlet fever, erysipelas, pneumonia caused by group A streptococci, furuncles, carbuncles caused by penicillin-sensitive Staphylococcus aureus, and angina. This product can also be used to treat leptospirosis, relapsing fever and early syphilis.

Indication: Due to the low blood concentration of this product, its application is limited to mild and moderate infections caused by pathogens that are highly sensitive to penicillin, such as tonsillitis, scarlet fever, erysipelas, pneumonia caused by group A streptococci, furuncles, carbuncles caused by penicillin-sensitive Staphylococcus aureus, and angina. This product can also be used to treat leptospirosis, relapsing fever and early syphilis.

Indication: Due to the low blood concentration of this product, its application is limited to mild and moderate infections caused by pathogens that are highly sensitive to penicillin, such as tonsillitis, scarlet fever, erysipelas, pneumonia caused by group A streptococci, furuncles, carbuncles caused by penicillin-sensitive Staphylococcus aureus, and angina. This product can also be used to treat leptospirosis, relapsing fever and early syphilis.

Indication: Due to the low blood concentration of this product, its application is limited to mild and moderate infections caused by pathogens that are highly sensitive to penicillin, such as tonsillitis, scarlet fever, erysipelas, pneumonia caused by group A streptococci, furuncles, carbuncles caused by penicillin-sensitive Staphylococcus aureus, and angina. This product can also be used to treat leptospirosis, relapsing fever and early syphilis.

Indication: Due to the low blood concentration of this product, its application is limited to mild and moderate infections caused by pathogens that are highly sensitive to penicillin, such as tonsillitis, scarlet fever, erysipelas, pneumonia caused by group A streptococci, furuncles, carbuncles caused by penicillin-sensitive Staphylococcus aureus, and angina. This product can also be used to treat leptospirosis, relapsing fever and early syphilis.