When the body's resistance is weakened or the antagonism between microorganisms loses balance, this fungus causes candidiasis. The occurrence of vulvar and vaginitis is related to pregnancy, diabetes, vulvar injury or maceration, oral contraceptives and immunosuppressive drugs such as antibiotics, changes in intercellular immunity or sugar metabolism during pregnancy, or rich vaginal epithelial sugar storage. When the glycogen in vaginal epithelial cells increases and the acidity increases, molds multiply rapidly and cause inflammation, so it is more common in pregnant women, patients with diabetes and those receiving estrogen treatment. Long-term use of antibiotics may inhibit other bacteria in the intestines or skin and lead to the activation of Candida.