Krabbe disease
Krabbe disease was first reported by Danish pediatrician Krabbe in 1916, hence the name Krabbe disease. Based on its clinical features, it is also called infantile familial diffuse sclerosis. It is an autosomal recessive metabolic disease with the mutant gene located on 14p. The genetic defect of Krabbe disease causes a deficiency of galactocerebroside-β-galactosidase, which is a genetic metabolic disease that mainly affects the white matter of the brain. The prognosis of this disease is extremely poor. Infantile-onset patients often die within 1 year of age. Late-onset patients can survive to around 10 years of age.
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Site of disease:
Brain Eyes -
Infectious :
Not contagious -
Frequent population:
Common in infants and young children -
Related symptoms:
Crossed legs Cerebellar ataxia Ankle clonus Convulsion Easy to cry -
Concurrent disease:
Related Drugs
Meclofenoxate Hydrochloride Capsules
Indication: Traumatic coma, alcohol poisoning, neonatal hypoxia, and enuresis in children.
Manufacturer:
Chengdu Leer Pharmaceutical Co., Ltd.
Related Ingredients
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2-(Dimethylamino)ethyl (4-chlorphenoxy)acetate list
51-68-3