Hyperaldosteronism in children
Primary hyperaldosteronism is caused by an increase in aldosterone produced by the zona glomerulosa of the adrenal cortex, which results in sodium retention, increased blood volume, and inhibition of plasma renin activity, with clinical symptoms such as hypertension and hypokalemia. It can be caused by hyperplasia or tumors of the zona glomerulosa cells of the adrenal glands. Hyperplasia is more common in children and is often bilateral. Tumors are mostly adenomas, which are more common on the left side. Patients with no abnormalities in the adrenal glands are called idiopathic hyperaldosteronism.
Related Drugs
Spironolactone
Indication: 1. Edema diseases: It is used in combination with other diuretics to treat edema diseases such as congestive edema, ascites caused by liver cirrhosis, and renal edema. The purpose is to correct the increased secondary aldosterone secretion associated with the above diseases and counteract the potassium excretion effect of other diuretics. It is also used to treat idiopathic edema; 2. Hypertension: It is an auxiliary drug for the treatment of hypertension; 3. It can be used for the diagnosis and treatment of primary aldosteronism; 4. Prevention of hypokalemia: It is used in combination with thiazide diuretics to enhance the diuretic effect and prevent hypokalemia.
Manufacturer:
Zhejiang Shenzhou Pharmaceutical Co., Ltd.
Spironolactone
Indication: 1. Edema diseases: It is used in combination with other diuretics to treat edema diseases such as congestive edema, ascites caused by liver cirrhosis, and renal edema. The purpose is to correct the increased secondary aldosterone secretion associated with the above diseases and counteract the potassium excretion effect of other diuretics. It is also used to treat idiopathic edema; 2. Hypertension: It is an auxiliary drug for the treatment of hypertension; 3. It can be used for the diagnosis and treatment of primary aldosteronism; 4. Prevention of hypokalemia: It is used in combination with thiazide diuretics to enhance the diuretic effect and prevent hypokalemia.
Manufacturer:
Tianjin Jinjin Pharmaceutical Co., Ltd.
Spironolactone
Indication: 1. Edema diseases: It is used in combination with other diuretics to treat edema diseases such as congestive edema, ascites caused by liver cirrhosis, and renal edema. The purpose is to correct the increased secondary aldosterone secretion associated with the above diseases and counteract the potassium excretion effect of other diuretics. It is also used to treat idiopathic edema; 2. Hypertension: It is an auxiliary drug for the treatment of hypertension; 3. It can be used for the diagnosis and treatment of primary aldosteronism; 4. Prevention of hypokalemia: It is used in combination with thiazide diuretics to enhance the diuretic effect and prevent hypokalemia.
Manufacturer:
Zhejiang Langhua Pharmaceutical Co., Ltd.