Congenital testicular dysgenesis in children
Congenital testicular dysgenesis, also known as Klinefetter syndrome, is a sex chromosome disease with a high incidence. Before chromosome identification, Klinefelter first reported this disease in 1942. Bradbury et al. showed that the patient's somatic cells showed female X chromatin in 1956. Jacobs and Strong first found that the chromosome karyotype of the patient was 47, XXY in 1959. It is more likely to occur in older women during pregnancy. Abnormal sex chromosomes lead to testicular dysgenesis, infertility, mental retardation, etc. The symptoms of this disease are not obvious before puberty, so it is not easy to detect early.
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Site of disease:
testis -
Infectious :
Not contagious -
Frequent population:
Children -
Related symptoms:
Testicular dysplasia vulva is immature and has no pubic hair testicles are tiny body development is slow during puberty testicular dysplasia -
Concurrent disease:
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Indication: Male: Testosterone replacement therapy for primary or secondary hypogonadism, such as: · after orchiectomy; · agenesis; · hypopituitarism; · endocrine impotence; · infertility caused by spermatogenesis disorders; · male menopausal symptoms, such as loss of libido, decreased mental and physical strength, etc. Female: Male gender reassignment: · masculinize females.
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Indication: No data yet
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