Hemophilus influenzae meningitis is more common in children, and its incidence is second only to meningococcal meningitis and pneumococcal meningitis, and is more common in infants aged 3 months to 3 years. Hemophilus influenzae is referred to as influenza bacillus, also known as Pfeiffer bacillus, Haemophilus influenzae, and Haemophilus influenzae. The bacteria can cause various infections in humans, such as conjunctivitis, otitis media, and upper respiratory tract infections, which are mostly caused by non-type b Haemophilus influenzae. Severe infections such as meningitis, epiglottitis, pericarditis, pneumonia, arthritis, osteomyelitis, sepsis, and facial cellulitis are mostly caused by type b Haemophilus influenzae (Hib). The proportion of purulent meningitis in children is 28.9%~51.7%, accounting for 1/3~1/2 of the proportion of purulent meningitis in children. Before the use of vaccines in European and American countries, it was the first pathogen in purulent meningitis in children. The clinical manifestations of encephalopathy caused by various bacteria are roughly the same, and can be summarized as manifestations of central infection, symptoms of increased intracranial pressure, and signs of meningeal irritation.