Rhinosporidiosis is a benign, chronic granulomatous infection caused by Rhinosporidiosis spp. that mainly invades the nose and nasal mucosa. The disease is prone to occur in tropical and subtropical areas, with more than 80% of cases occurring in India and Sri Lanka, and the rest in Brazil and Argentina in South America. In China, it was first reported by Li Xinzhang in 1979. It is mostly caused by contact with water or soil contaminated by the bacteria. It is more common in children and young people, more common in boys than in girls, and most commonly occurs in the nose, accounting for about 72% of all patients. It is papillary at first, with a wrinkled surface like a wart, gradually increasing in size, with a pedicle or tumor-like base, and mucus-like accumulation in the tumor, such as a mucocele. It is not difficult to diagnose by finding a huge sporangium in the smear. Trivalent or pentavalent antimony compounds, dapsone, and topical 2% tartar emetic can be used to treat this disease.