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1,3,5-Triazine-2,4-diamine, 6-(2,5-dichlorophenyl)-, (2Z)-2-butenedioate (1:1) Registered Holders
1,3,5-Triazine-2,4-diamine, 6-(2,5-dichlorophenyl)-, (2Z)-2-butenedioate (1:1) structure
1,3,5-Triazine-2,4-diamine, 6-(2,5-dichlorophenyl)-, (2Z)-2-butenedioate (1:1)
Irsogladine is a PDE4 inhibitor and muscarinic acetylcholine receptor binder.Target: PDE4; mACHRIrsogladine treatment (300 and 500 mg/kg/day) resulted in a dose-dependent reduction of angiogenesis in wild-type mice by 21 and 45.3% (P < 0.02, P < 0.001), in tPA-deficient mice by 42.6 and 46% (P < 0.001, P < 0.001), and in uPA-deficient mice by 27.2 and 46% (P < 0.05, p < 0.001), respectively. Irsogladine inhibits bFGF-induced angiogenesis in wild-type, tPA-knockout, and uPA-knockout mice
Find 5 Related Holders
Zhejiang Haizhou Pharmaceutical Co., Ltd.
China
China
API Registration Country
API Active
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Founded in:
1997-08-11 -
Country:
China -
Address:
Coastal Industrial Park, Linhai City, Zhejiang Province -
Tax NO.:
913310822552307565 -
Registered Funds:
50.88 million yuan -
Website:
-
Email:
Jiangxi Pharmaceutical Co., Ltd.
China
China
API Registration Country
API Active
-
Founded in:
1996-06-10 -
Country:
China -
Address:
No. 758, Huiren West Avenue, Xiaolan Industrial Park, Nanchang County, Nanchang City, Jiangxi Province -
Tax NO.:
913600001582615429 -
Registered Funds:
295.8 million yuan -
Website:
-
Email:
Qilu Pharmaceutical Co., Ltd.
China
China
API Registration Country
API Active
-
Founded in:
1992-08-21 -
Country:
China -
Address:
No. 317, Xinluo Street, High-tech Zone, Jinan City, Shandong Province -
Tax NO.:
91370000614073351Q -
Registered Funds:
600 million yuan -
Website:
-
Email:
Liaoning Tianlong Pharmaceutical Co., Ltd.
China
China
API Registration Country
API Active
-
Founded in:
1992-07-25 -
Country:
China -
Address:
Panjin Economic Development Zone -
Tax NO.:
91211103604381019Q -
Registered Funds:
50 million yuan -
Website:
-
Email:
Hebei Guangxiang Pharmaceutical Co., Ltd.
China
China
API Registration Country
API Inactive
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Founded in:
2017-02-28 -
Country:
China -
Address:
West District of Cangzhou Lingang Economic and Technological Development Zone, east side of Jingliu Road -
Tax NO.:
91130931MA08897J29 -
Registered Funds:
930 million yuan -
Email:
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