Dolasetron mesylate structure
Dolasetron mesylate
Dolasetron was launched as Anzemet in Australia and the US for the
prevention of nausea and vomiting in chemotherapy patients. It is a highly potent
and very selective antagonist of 5-HT3 receptors ; it is the sixth in this class of
compounds to be marketed for the treatment of chemotherapy-induced emesis.
The last two approved in this class were Nazasetron (1994) and Ramosetron
(1996). Anzemet was prepared by a seven step sequence from a
cyclopentenecarboxylic ester via a Robinson-Schopf
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EMCURE PHARMACEUTICALS LTD
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USV PRIVATE LIMITED
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Haisco Pharmaceutical(Meishan) Co., Ltd.
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Chengdu Sino-Strong Pharmaceutical Co., Ltd.
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APOTEX PHARMACHEM INDIA PVT LTD
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ROLABO OUTSOURCING SL
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Jiangsu Yongan Pharmaceutical Co., Ltd.
China
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No. 18, Provincial Highway 237, Huai'an Economic Development Zone, Jiangsu -
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USV LTD
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