Inhibit the growth of intestinal pathogens and improve the intestinal microecological environment

Significantly inhibit ovulation and prevent fertilized eggs from implanting, and increase the consistency of cervical mucus and the resistance of sperm penetration, thus playing a quick-acting contraceptive role

Dihydropyridine calcium antagonists can selectively inhibit the transmembrane transport of calcium ions into myocardial cells and smooth muscle cells, and inhibit the release of calcium ions from intracellular pools without changing the plasma calcium ion concentration. Pharmacological actions include: 1. It can simultaneously dilate the coronary arteries in the normal blood supply area and the ischemic area, antagonize coronary artery spasm, increase myocardial oxygen delivery, relieve and prevent coronary artery spasm; 2. It can inhibit myocardial contraction, reduce myocardial metabolism, and reduce myocardial oxygen consumption; 3. It can dilate peripheral resistance vessels, reduce peripheral resistance, and reduce cardiac afterload; 4. It can delay the sinus node function and atrioventricular conduction of the isolated heart, but electrophysiological studies of whole animals and humans have not found that it has the effect of delaying atrioventricular conduction, prolonging the recovery time of the sinus node, and slowing down the sinus node rate.

(1) Analgesic effect: It is mainly through inhibiting the synthesis of prostaglandins and other substances that can make pain sensitive to mechanical or chemical stimulation (such as bradykinin, histamine), and is a peripheral analgesic. However, the possibility of central analgesia (possibly acting on the hypothalamus) cannot be ruled out. (2) Anti-inflammatory effect: The exact mechanism is still unclear. It may be due to the fact that this product acts on inflamed tissues and inhibits the synthesis of prostaglandins or other substances that can cause inflammatory reactions (such as histamine) to exert an anti-inflammatory effect. Inhibition of the release of lysosomal enzymes and leukocyte chemotaxis may also be related to it. (3) Antipyretic effect: It may act on the hypothalamic temperature regulation center to cause peripheral vasodilation, increased skin blood flow, sweating, and increased heat dissipation to exert an antipyretic effect. This central effect may be related to the inhibition of prostaglandin synthesis in the hypothalamus. (4) Anti-rheumatic effect: The anti-rheumatic mechanism of this product, in addition to antipyretic and analgesic effects, is mainly anti-inflammatory. (5) Inhibit platelet aggregation: It works by inhibiting platelet cyclooxygenase and reducing the production of prostaglandins.

Anticonvulsant, anti-epileptic, anti-neuropathic pain, anti-manic-depressive, improves the symptoms of certain mental illnesses, and treats central diabetes insipidus; the mechanisms include use-dependent blocking of various excitable cell membrane Na channels, inhibition of T-type calcium channels, enhancement of central noradrenergic nerve activity, promotion of antidiuretic hormone (ADH) secretion, or increased sensitivity of effectors to ADH.