This product is an aminoglycoside antibiotic that has good antibacterial effects on various Gram-negative and Gram-positive bacteria. The mechanism of action is to bind to the 30S subunit of the bacterial ribosome and inhibit the synthesis of bacterial proteins. In recent years, the number of Gram-negative bacteria resistant to gentamicin has increased significantly.

This product is an antibiotic drug. Except for enterococci, methicillin-resistant and penicillin-resistant Staphylococcus aureus, it has good antibacterial activity against other Gram-positive cocci. Pneumococci and lytic streptococci are highly sensitive to this product. Diphtheria Corynebacterium, anthrax Bacillus, Listeria and Clostridium are sensitive to this drug. This product has stronger antibacterial activity against Escherichia coli, Proteus mirabilis and Klebsiella pneumoniae than cephalothin and cefotaxime, but its antibacterial effect against Pseudomonas aeruginosa is worse than the latter two. Salmonella typhi and Shigella are sensitive to this drug, while other Enterobacteriaceae, Acinetobacter and Pseudomonas aeruginosa and Bacteroides fragilis are resistant. Neisseria is quite sensitive to this product, while influenza bacilli are only moderately sensitive.

This product is an antibiotic drug. Except for enterococci, methicillin-resistant and penicillin-resistant Staphylococcus aureus, it has good antibacterial activity against other Gram-positive cocci. Pneumococci and lytic streptococci are highly sensitive to this product. Diphtheria Corynebacterium, anthrax Bacillus, Listeria and Clostridium are sensitive to this drug. This product has stronger antibacterial activity against Escherichia coli, Proteus mirabilis and Klebsiella pneumoniae than cephalothin and cefotaxime, but its antibacterial effect against high-content bacteria is weaker than the latter two. Salmonella typhi and Shigella are sensitive to this drug, while other Enterobacteriaceae, Acinetobacter and Pseudomonas aeruginosa and Bacteroides fragilis are resistant. Neisseria is quite sensitive to this product, while influenza bacilli are only moderately sensitive.

Intraperitoneal injection of the drug into mice with cholestatic jaundice induced by 1-naphthyl isothiocyanate can reduce serum aspartate aminotransferase, alanine aminotransferase and serum conjugated bilirubin levels, and alleviate liver cell damage in the model animals.

It can inhibit cyclooxygenase, reduce the synthesis of prostaglandins, and has antipyretic, analgesic and anti-inflammatory effects.