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Shanghai Livzon Pharmaceutical Co., Ltd.
  • Founded in:

    1995-04-11
  • Country:

    China China
  • Address:

    No. 1150, Guiqiao Road, China (Shanghai) Pilot Free Trade Zone
  • Tax NO.:

    913100001338549664
  • Registered Funds:

    87.3289 million yuan
  • Email:

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Inorganic and small molecule organic substances obtained from fresh calf blood

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Name Description Content CAS NO. Registered Holders
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1. Mechanism of action: Repeated administration of large doses of LH-RH or its highly active derivative leuprolide acetate can produce a transient excitatory effect on the pituitary-gonadal system (acute effect) immediately after the first dose, and then inhibit the pituitary gland from producing and releasing gonadotropins, further reducing the production of estradiol and testosterone (chronic effect). 2. Inhibitory effect on gonadal hormone concentrations: (1) For patients with endometriosis, uterine fibroids or premenopausal breast cancer, it can reduce serum estradiol to levels close to menopausal levels, inhibit ovarian function, inhibit normal ovulation and stop menstruation. (2) For patients with prostate cancer, it can reduce serum testosterone concentrations to below castration levels, indicating a drug-induced castration effect. (3) For boys and girls with central precocious puberty, it can reduce serum gonadotropin levels to prepubertal levels, and have a progressive inhibitory effect on secondary sexual characteristics.

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