Chongqing Lummy Pharmaceutical Co., Ltd.

This product is an opioid receptor antagonist, which has almost no pharmacological activity itself, but can competitively antagonize various opioid receptors and has a strong affinity for m receptors. It can completely or partially correct the central inhibitory effects of opioid substances, such as respiratory depression, sedation and hypotension; it has a wake-up effect on animals with acute ethanol poisoning; it is a pure opioid receptor antagonist and does not cause respiratory depression, psychotomimetic reactions or miotic reactions; there is no drug resistance, nor physiological or mental dependence.

It can antagonize histamine and acetylcholine, relieve bronchospasm and have an anti-asthmatic effect; it also has a strong inhibitory effect on the cough center; it can cause increased secretions, thin thick sputum, reduce sputum viscosity, and make it easier to cough up; it has a similar effect to aminophylline in relaxing bronchial smooth muscles; it can also increase the electrical stimulation threshold of the cerebral cortex, inhibit the synaptic conduction of electrical stimulation and the spread of epileptic electricity.

This product belongs to the lincomycin antibiotics, which is a derivative of lincomycin. Its antibacterial activity is 4 to 8 times stronger than that of lincomycin. It has high antibacterial activity against Gram-positive bacteria such as Staphylococcus (including penicillin-resistant strains), Streptococcus, Corynebacterium diphtheriae, Bacillus anthracis, etc. It also has good antibacterial activity against Gram-negative anaerobic bacteria. Most of the Bacteroides, including Bacteroides fragilis, Fusobacterium, Peptococcus, Peptostreptococcus, and Clostridium perfringens, are highly sensitive to this product. Gram-negative aerobic bacteria, including Haemophilus influenzae, Neisseria, and Mycoplasma, are resistant to this product. There is no cross-resistance between this product and penicillin, chloramphenicol, cephalosporins, and tetracyclines. It has partial cross-resistance with macrolides and complete cross-resistance with lincomycin. The mechanism of action of this product is to bind to the 50S subunit of the bacterial ribosome, prevent the extension of the peptide chain, and thus inhibit the protein synthesis of bacterial cells. This product is an antibacterial drug, but at high concentrations, it also has a bactericidal effect on certain bacteria.

This product belongs to the lincomycin antibiotics, which is a derivative of lincomycin. Its antibacterial spectrum is the same as that of lincomycin, and its antibacterial activity is 4 to 8 times stronger than that of lincomycin. It has high antibacterial activity against Gram-positive bacteria such as Staphylococcus (including penicillin-resistant strains), Streptococcus, Corynebacterium diphtheriae, Bacillus anthracis, etc. It also has good antibacterial activity against Gram-negative anaerobic bacteria. Most of the Bacteroides, including Bacteroides fragilis, Fusobacterium, Peptococcus, Peptostreptococcus, and Clostridium perfringens, are highly sensitive to this product. Gram-negative aerobic bacteria, including Haemophilus influenzae, Neisseria, and Mycoplasma, are resistant to this product. There is no cross-resistance between this product and penicillin, chloramphenicol, cephalosporins, and tetracyclines, but it has partial cross-resistance with macrolides and complete cross-resistance with lincomycin. The mechanism of action of this product is to bind to the 50S subunit of the bacterial ribosome, prevent the elongation of the peptide chain, and thus inhibit the protein synthesis of bacterial cells. This product is an antibacterial drug, but at high concentrations, it also has a bactericidal effect on certain bacteria.

It has high antibacterial activity against common aerobic Gram-positive bacteria, such as Staphylococcus aureus (including those resistant to penicillin G), Staphylococcus epidermidis, beta-hemolytic Streptococcus, viridans Streptococcus and Streptococcus pneumoniae. It has good antibacterial effect on anaerobic bacteria, including Clostridium diphtheriae, and Clostridium perfringens. It has no activity against Gram-negative bacteria such as Enterococcus, meningococci, Neisseria gonorrhoeae, and Haemophilus influenzae, as well as fungi. There is no cross-resistance with penicillin, chloramphenicol, cephalosporins and tetracyclines, and there is partial cross-resistance with macrolides. It acts on the 50S subunit of the ribosome of sensitive bacteria, preventing the extension of the peptide chain, thereby inhibiting the protein synthesis of bacterial cells. It is generally an antibacterial agent, but at high concentrations, it also has a bactericidal effect on certain bacteria.