Pyogenic spondylitis is not very rare, but acute onset only accounts for about 50%, and half of the patients have a subacute or chronic process. Due to different clinical manifestations, different affected parts, and different symptoms and signs, it is often misdiagnosed or missed. Common pathogens are Staphylococcus aureus, Staphylococcus aureus, Streptococcus and Pseudomonas aeruginosa. The most common route of infection is hematogenous infection. The second is spinal surgery, lumbar puncture, local open injury, etc. directly causing spinal infection. A few are spread from infection foci adjacent to the spine, such as abscesses, bedsores, etc. Patients are mostly young and middle-aged people aged 20 to 40. Men are about 4 times more likely to be infected than women.